Insights into Glomerular Filtration and Albuminuria

被引：134

作者：

Benzing, Thomas ^{[1
,2
,3
,4
]}

Salant, David ^{[5
,6
]}

机构：

[1] Univ Cologne, Dept Internal Med 2, Fac Med, Cologne, Germany

[2] Univ Cologne, Ctr Mol Med Cologne, Fac Med, Cologne, Germany

[3] Univ Cologne, Univ Hosp Cologne, Cologne, Germany

[4] Univ Cologne, Excellence Cluster CECAD, Cologne, Germany

[5] Boston Med Ctr, Nephrol Sect, Dept Med, Boston, MA USA

[6] Boston Univ, Sch Med, Boston, MA 02118 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2021年 / 384卷 / 15期

关键词：

CONGENITAL NEPHROTIC SYNDROME; KIDNEY-DISEASE; MECHANICAL CHALLENGES; TYROSINE KINASE-1; NEPHRIN LOCALIZES; BASEMENT-MEMBRANE; EPITHELIAL-CELL; CAPILLARY WALL; PODOCYTE LOSS; PERMEABILITY;

D O I：

10.1056/NEJMra1808786

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a disordered kidney filtration barrier within glomeruli. This review describes the roles of glomerular capillary pressure, the glomerular basement membrane, and podocytes in regulating glomerular filtration and permeability.

引用

页码：1437 / 1446

页数：10

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