An emerging role for endothelial nitric oxide synthase in chronic inflammation and cancer

被引：230

作者：

Ying, Lei ^{[1
]}

Hofseth, Lorne J. ^{[1
]}

机构：

[1] Univ S Carolina, Coll Pharm, Dept Basic Pharmaceut Sci, Columbia, SC 29208 USA

来源：

CANCER RESEARCH | 2007年 / 67卷 / 04期

关键词：

D O I：

10.1158/0008-5472.CAN-06-2149

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Nitric oxide (NO) is a free radical that is involved in carcinogenesis. Recent literature indicates that endothelial NO synthase (eNOS) can modulate cancer-related events (angiogenesis, apoptosis, cell cycle, invasion, and metastasis). We review the literature linking eNOS to carcinogenesis to encourage future research assessing the role of eNOS in cancer prevention and treatment.

引用

页码：1407 / 1410

页数：4

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