P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis

被引：38

作者：

Jeong, Yeon Hee

Chung, Soo Yeon

Han, Ah-Reum

Sung, Min Kyung

Jang, Dae Sik

Lee, Jun

Kwon, Youngjoo

Lee, Hwa Jeong ^{[1
]}

Seo, Eun-Kyoung

机构：

[1] Ewha Womans Univ, Coll Pharm, Seoul 120750, South Korea

[2] Korea Inst Oriental Med, Dept Herbal Pharmaceut Dev, Taejon 305812, South Korea

来源：

CHEMISTRY & BIODIVERSITY | 2007年 / 4卷 / 01期

关键词：

D O I：

10.1002/cbdv.200790001

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

(-)-Syringaresinol and tricin, isolated from the AcOEt-soluble extract of the whole plants of Sasa borealis (Gramineae), showed inhibitory effects on the P-glycoprotein in adriamycin-resistant human breast cancer cells, MCF-7/ADR.

引用

页码：12 / 16

页数：5

共 20 条

[1] A highly bioactive lignophenol derivative from bamboo lignin exhibits a potent activity to suppress apoptosis induced by oxidative stress in human neuroblastoma SH-SY5Y cells [J].

Akao, Y ;

Seki, N ;

Nakagawa, Y ;

Yi, H ;

Matsumoto, K ;

Ito, Y ;

Ito, K ;

Funaoka, M ;

Maruyama, W ;

Naoi, M ;

Nozawa, Y .

BIOORGANIC & MEDICINAL CHEMISTRY, 2004, 12 (18) :4791-4801

[2]

Das B., 1999, Fitoterapia, V70, P101, DOI 10.1016/S0367-326X(98)00014-8

[3] The P-glycoprotein multidrug transporter [J].

Fardel, O ;

Lecureur, V ;

Guillouzo, A .

GENERAL PHARMACOLOGY, 1996, 27 (08) :1283-1291

[4] The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinorna MCF-7/adr cells [J].

Fu, LW ;

Zhang, YM ;

Liang, YJ ;

Yang, XP ;

Pan, QC .

EUROPEAN JOURNAL OF CANCER, 2002, 38 (03) :418-426

[5]

HARKER WG, 1985, CANCER RES, V45, P4091

[6] Transcriptional regulators of the human multidrug resistance 1 gene: recent views [J].

Labialle, S ;

Gayet, L ;

Marthinet, E ;

Rigal, D ;

Baggetto, LG .

BIOCHEMICAL PHARMACOLOGY, 2002, 64 (5-6) :943-948

[7] Phenanthrene and other aromatic constituents of Bulbophyllum vaginatum [J].

Leong, YW ;

Harrison, LJ ;

Powell, AD .

PHYTOCHEMISTRY, 1999, 50 (07) :1237-1241

[8] Membrane cholesterol contents influence the protective effects of quercetin and rutin in erythrocytes damaged by oxidative stress [J].

Lopez-Revuelta, Abel ;

Sanchez-Gallego, Jose I. ;

Hernandez-Hernandez, Angel ;

Sanchez-Yague, Jesus ;

Llanillo, Marcial .

CHEMICO-BIOLOGICAL INTERACTIONS, 2006, 161 (01) :79-91

[9]

NAMBA T, 1982, Shoyakugaku Zasshi, V36, P43

[10] The study of the quercetin action on human erythrocyte membranes [J].

Pawlikowska-Pawlega, B ;

Gruszecki, WI ;

Misiak, LE ;

Gawron, A .

BIOCHEMICAL PHARMACOLOGY, 2003, 66 (04) :605-612

← 1 2 →