Recent advances in hydride transfer-involved C(sp3)-H activation reactions

被引：89
作者：
An, Xiao-De [1 ]
Xiao, Jian [1 ,2 ]
机构：
[1] Qingdao Agr Univ, Coll Chem & Pharmaceut Sci, Qingdao 266109, Peoples R China
[2] Qingdao Agr Univ, Coll Marine Sci & Engn, Qingdao 266109, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2021年 / 8卷 / 06期
关键词：
Scaffolds; -; Hydrides;
D O I：
10.1039/d0qo01502d
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The hydride transfer reaction, which is characterized by a redox-neutral and step/atom economic process, has emerged as an enabling platform for C(sp(3))-H activation with high efficiency. During the past five years, significant advances have been made in new versions of hydride transfer-enabled C(sp(3))-H activation, which mainly include the construction of novel scaffolds for cycles, and the intermolecular methods of both hydride transfer and C(sp(3))-H functionalization. Herein, we summarize recent progress according to the reaction types categorized into hydride transfer/intramolecular C(sp(3))-H functionalization, hydride transfer/intermolecular C(sp(3))-H functionalization, and hydride reduction reactions. Furthermore, unsolved scientific problems as well as future directions in this field are also directly indicated. This review covers the period from 2016 to 2020.
引用
收藏
页码：1364 / 1383
页数：20
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