DNA migration and separation on surfaces with a microscale dielectrophoretic trap array

被引：12
|
作者：
Petersen, Eric
Li, Bingquan [1 ]
Fang, Xiaohua
Luo, Haobin
Samuilov, Vladimir
Gersappe, Dilip
Sokolov, Jonathan
Chu, Benjamin
Rafailovich, Miriam
机构：
[1] Harvard Univ, Cambridge, MA 02138 USA
[2] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA
[3] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA
来源：
PHYSICAL REVIEW LETTERS | 2007年 / 98卷 / 08期
关键词：
D O I：
10.1103/PhysRevLett.98.088102
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.
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页数：4
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