DNA migration and separation on surfaces with a microscale dielectrophoretic trap array

被引：12
|
作者：
Petersen, Eric
Li, Bingquan [1 ]
Fang, Xiaohua
Luo, Haobin
Samuilov, Vladimir
Gersappe, Dilip
Sokolov, Jonathan
Chu, Benjamin
Rafailovich, Miriam
机构：
[1] Harvard Univ, Cambridge, MA 02138 USA
[2] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA
[3] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA
来源：
PHYSICAL REVIEW LETTERS | 2007年 / 98卷 / 08期
关键词：
D O I：
10.1103/PhysRevLett.98.088102
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.
引用
收藏
页数：4
相关论文
共 50 条
  • [21] DIRECTED MIGRATION OF MICROSCALE SWIMMERS BY AN ARRAY OF SHAPED OBSTACLES: MODELING AND SHAPE OPTIMIZATION
    Tong, Jiajun
    Shelley, Michael J.
    SIAM JOURNAL ON APPLIED MATHEMATICS, 2018, 78 (05) : 2370 - 2392
  • [22] Microscale topographic surfaces modulate three-dimensional migration of human spermatozoa
    Huang, Gui
    Li, Sun
    Jin, Xueqing
    Qi, Meng
    Gong, Xiangjun
    Zhang, Guangzhao
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2020, 193
  • [23] Continuous Concentration and Separation of Microparticles Using Dielectrophoretic Force in a V-Shaped Electrode Array
    Hayashi, Masahito
    Kaneko, Tomoyuki
    Yasuda, Kenji
    JAPANESE JOURNAL OF APPLIED PHYSICS, 2011, 50 (06)
  • [24] Separation of DNA using ferrofluid array electrophoresis
    Mayer, P
    Bibette, J
    Viovy, JL
    STATISTICAL MECHANICS IN PHYSICS AND BIOLOGY, 1997, 463 : 57 - 66
  • [25] Polarizability of Six-Helix Bundle and Triangle DNA Origami and Their Escape Characteristics from a Dielectrophoretic Trap
    Gan, Lin
    Camacho-Alanis, Fernanda
    Ros, Alexandra
    ANALYTICAL CHEMISTRY, 2015, 87 (24) : 12059 - 12064
  • [26] Patterned Hybrid Nanohole Array Surfaces for Cell Adhesion and Migration
    Westcott, Nathan P.
    Lou, Yi
    Muth, John F.
    Yousaf, Muhammad N.
    LANGMUIR, 2009, 25 (19) : 11236 - 11238
  • [27] ChipCE™:: A silicon microsystem for migration, separation and detection of DNA
    Shastry, A
    Lal, R
    MEMS-03: IEEE THE SIXTEENTH ANNUAL INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, 2003, : 427 - 430
  • [28] Separation of DNA with different configurations on flat and nanopatterned surfaces
    Li, Bingquan
    Fang, Xiaohua
    Luo, Haobin
    Seo, Young-Soo
    Petersen, Eric
    Ji, Yuan
    Rafailovich, Miriam
    Sokolov, Jonathan
    Gersappe, Dilip
    Chu, Benjamin
    ANALYTICAL CHEMISTRY, 2006, 78 (14) : 4743 - 4751
  • [29] Mechanisms of DNA separation in entropic trap arrays: a Brownian dynamics simulation
    Streek, M
    Schmid, F
    Duong, TT
    Ros, A
    JOURNAL OF BIOTECHNOLOGY, 2004, 112 (1-2) : 79 - 89
  • [30] DNA Manipulation and Separation in Sublithographic-Scale Nanowire Array
    Yasui, Takao
    Rahong, Sakon
    Motoyama, Koki
    Yanagida, Takeshi
    Wu, Qiong
    Kaji, Noritada
    Kanai, Masaki
    Doi, Kentaro
    Nagashima, Kazuki
    Tokeshi, Manabu
    Taniguchi, Masateru
    Kawano, Satoyuki
    Kawai, Tomoji
    Baba, Yoshinobu
    ACS NANO, 2013, 7 (04) : 3029 - 3035
12345