DNA migration and separation on surfaces with a microscale dielectrophoretic trap array

被引：12

作者：

Petersen, Eric

Li, Bingquan ^{[1
]}

Fang, Xiaohua

Luo, Haobin

Samuilov, Vladimir

Gersappe, Dilip

Sokolov, Jonathan

Chu, Benjamin

Rafailovich, Miriam

机构：

[1] Harvard Univ, Cambridge, MA 02138 USA

[2] SUNY Stony Brook, Dept Mat Sci & Engn, Stony Brook, NY 11794 USA

[3] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA

来源：

PHYSICAL REVIEW LETTERS | 2007年 / 98卷 / 08期

关键词：

D O I：

10.1103/PhysRevLett.98.088102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We studied the surface migration of DNA chains driven by a dc electric field across localized dielectrophoretic traps. By adjusting the length scale of the trap array, separation of a selected band of DNA was accomplished with a scaling exponent between mobility and number of base pairs similar to that obtained in capillary electrophoresis. We then provided a model, which predicts the trapping and extension of DNA chains at a dielectrophoretic trap responsible for the surface mobility and separation.

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页数：4

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