Timeline - Conrad Hal Waddington: the last renaissance biologist?

被引：147

作者：

Slack, JMW ^{[1
]}

机构：

[1] Univ Bath, Dept Biol & Biochem, Dev Biol Programme, Bath BA2 7AY, Avon, England

来源：

NATURE REVIEWS GENETICS | 2002年 / 3卷 / 11期

关键词：

D O I：

10.1038/nrg933

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Conrad Hal Waddington was a leading embryologist and geneticist from the 1930s to the 1950s. He is remembered mainly for his concepts of the 'epigenetic landscape' and 'genetic assimilation'. This article reviews his life and work, and enquires to what extent his ideas are relevant tools for understanding the biological problems of today.

引用

页码：889 / 895

页数：8

共 21 条

[1]

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[2]

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[3]

Spemann H., Mangold H., Über induktion von embryonenanlagen durch implantation artfremder organisatoren, Arch. Microsk. Anat. EntwMech., 100, pp. 599-638, (1924)

[4]

Waddington C.H., Experiments on the development of chick and duck embryos cultivated in vitro, Phil. Trans. R. Soc. Lond. B Biol. Sci., 221, pp. 179-230, (1932)

[5]

Waddington C.H., Experiments on determination in the rabbit embryo, Arch. Biol., 48, pp. 273-290, (1937)

[6]

Bautzmann H., Holtfreter J., Spemann H., Mangold O., Versuche zur analyse der induktionsmittel in der embryonalentwicklung, Naturwissenschaften, 20, pp. 971-974, (1932)

[7]

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[8]

Dalcq A., Pasteels J., Une conception nouvelle des bases physiologique de la morphogènèse, Arch. Biol., 48, pp. 669-710, (1937)

[9]

Waddington C.H., Needham J., Needham D.M., Studies on the nature of the amphibian organisation centre. I. Chemical properties of the evocator, Proc. R. Soc. Lond. B Biol. Sci., 117, pp. 289-310, (1935)

[10]

Waddington C.H., Needham J., Brachet J., Studies on the nature of the amphibian organisation centre. III. The activation of the evocator, Proc. R. Soc. Lond. B Biol. Sci., 120, pp. 173-198, (1936)

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