Role of Immunofluorescence and Electron Microscopy in the Evaluation of Renal Biopsies in Nephrotic Syndrome in a Developing Country

被引：16

作者：

Mubarak, Muhammed ^{[1
]}

Kazi, Javed Iqbal ^{[1
]}

机构：

[1] Sindh Inst Urol & Transplantat, Dept Histopathol, Karachi, Pakistan

来源：

ULTRASTRUCTURAL PATHOLOGY | 2009年 / 33卷 / 06期

关键词：

electron microscopy; immunofluorescence; morphological patterns; nephrotic syndrome; renal biopsy; GLOMERULAR-DISEASE; DIAGNOSIS; SPECIMENS;

D O I：

10.3109/01913120903296952

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

To determine the role of immunofluorescence (IF) and electron microscopy (EM) in the evaluation of renal biopsies in a developing country, the authors carried out a study in 200 patients with nephrotic syndrome. Renal biopsies were studied by light microscopy, IF, and EM. IF study was useful in all, being essential in 23.5% and helpful in remaining cases. EM was useful in 94.5% cases, being essential in 43% and helpful in 51.5% cases. The results demonstrate that IF and EM are essential in the evaluation of renal biopsies in nephrotic syndrome and these should be employed in the pathologic evaluation of renal biopsies.

引用

页码：260 / 264

页数：5

共 24 条

[1] Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues; an adjunct for diagnosis of glomerulonephritis [J].

Chowdhury, ARH ;

Ehara, T ;

Higuchi, M ;

Hora, K ;

Shigematsu, H .

NEPHROLOGY, 2005, 10 (03) :298-304

[2]

Churg J, 1995, RENAL DIS CLASSIFICA, P1

[3] Value of electron microscopy in kidney biopsy diagnosis [J].

Collan, Y ;

Hirsimäk, P ;

Aho, H ;

Wuorela, M ;

Sundström, J ;

Tertti, R ;

Metsärinne, K .

ULTRASTRUCTURAL PATHOLOGY, 2005, 29 (06) :461-468

[4] Approach to renal biopsy [J].

Fogo, AB .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2003, 42 (04) :826-836

[5] Electron microscopy and immunocytochemistry in the assessment of renal biopsy specimens: Actual and optimal practice [J].

Furness, PN ;

Boyd, S .

JOURNAL OF CLINICAL PATHOLOGY, 1996, 49 (03) :233-237

[6] Renal biopsy specimens [J].

Furness, PN .

JOURNAL OF CLINICAL PATHOLOGY, 2000, 53 (06) :433-438

[7]

Furness PN, 1998, J NEPHROL UROL TRANS, V1, P19

[8]

Haas M, 1997, J AM SOC NEPHROL, V8, P70

[9]

Jamal Q, 1988, J Pak Med Assoc, V38, P272

[10] Spectrum of glomerulonephritides in adults with nephrotic syndrome in Pakistan [J].

Kazi, Javed Iqbal ;

Mubarak, Muhammed ;

Ahmed, Ejaz ;

Akhter, Fazal ;

Naqvi, Syed Ali Anwer ;

Rizvi, Syed Adeebul Hassan .

CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2009, 13 (01) :38-43

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