Enhancing sensitivity of a whispering gallery mode biosensor by subwavelength confinement

被引:44
作者
Gaathon, O. [1 ]
Culic-Viskota, J. [1 ]
Mihnev, M. [1 ]
Teraoka, I. [1 ]
Arnold, S. [1 ]
机构
[1] Polytech Univ, Microparticle Photophys Lab, Brooklyn, NY 11201 USA
基金
美国国家科学基金会;
关键词
D O I
10.1063/1.2397017
中图分类号
O59 [应用物理学];
学科分类号
摘要
The authors demonstrate enhanced sensitivity of a spherical whispering gallery mode biosensor (WGMB) by confining orbiting light near the surface using a subwavelength (sub-lambda) high refractive index layer on a fluorine doped silica microsphere (radius R similar to 200 mu m). Their experiments at a free space wavelength lambda similar to 1310 nm show that the frequency shift sensitivity by changing the external refractive index is increased by more than 700% by adding a 340 nm thick polystyrene layer. This advance is expected to move the WGMB well into the lead as the most sensitive method for unlabeled biosensing.
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页数:3
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