Molybdenum-based hetero-nanocomposites for cancer therapy, diagnosis and biosensing application: Current advancement and future breakthroughs

被引：61

作者：

Dhas, Namdev ^{[1
]}

Kudarha, Ritu ^{[2
]}

Garkal, Atul ^{[1
]}

Ghate, Vivek ^{[3
]}

Sharma, Shilpa ^{[4
]}

Panzade, Prabhakar ^{[5
]}

Khot, Shubham ^{[6
]}

Chaudhari, Pinal ^{[3
]}

Singh, Ashutosh ^{[7
]}

Paryani, Mitali ^{[1
]}

Lewis, Shaila ^{[3
]}

Garg, Neha ^{[8
]}

Singh, Narinder ^{[4
]}

Bangar, Priyanka ^{[9
]}

Mehta, Tejal ^{[1
]}

机构：

[1] Nirma Univ, Inst Pharm, Dept Pharmaceut, Ahmadabad 382481, Gujarat, India

[2] Maharaja Sayajirao Univ Baroda, Fac Pharm, Vadodara 390002, Gujarat, India

[3] Manipal Acad Higher Educ MAHE, Manipal Coll Pharmaceut Sci, Dept Pharmaceut, Manipal 576104, Karnataka, India

[4] Indian Inst Technol, Dept Chem, Rupnagar 140001, Punjab, India

[5] Dr Babasaheb Ambedkar Technol Univ, Srinath Coll Pharm, Dept Pharmaceut, Aurangabad 431133, Maharashtra, India

[6] Sinhgad Inst Pharm, Pune 411041, Maharashtra, India

[7] Indian Inst Technol, Sch Basic Sci, Kamand 175005, Himachal Prades, India

[8] BHU, Inst Med Sci, Fac Ayurveda, Dept Med Chem, Varanasi 221005, Uttar Pradesh, India

[9] Intas Pharmaceut Ltd, Ahmadabad 382213, Gujarat, India

来源：

JOURNAL OF CONTROLLED RELEASE | 2021年 / 330卷

关键词：

Molybdenum disulphide; Phototherapy; Biomedical applications; Chemotherapy; Magnetic resonance imaging; Photoacoustic imaging; TRANSITION-METAL DICHALCOGENIDES; MESOPOROUS SILICA NANOPARTICLES; ANTIDIABETIC DRUG METFORMIN; CHEMO-PHOTOTHERMAL THERAPY; LAYER MOS2 NANOSHEETS; ONE-POT SYNTHESIS; PHOTODYNAMIC THERAPY; PROSTATE-CANCER; IN-VITRO; GOLD NANOPARTICLES;

D O I：

10.1016/j.jconrel.2020.12.015

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In recent years, there have been significant advancements in the nanotechnology for cancer therapy. Even though molybdenum disulphide (MoS2)-based nanocomposites demonstrated extensive applications in biosensing, bioimaging, phototherapy, the review article focusing on MoS2 nanocomposite platform has not been accounted for yet. The review summarizes recent strategies on design and fabrication of MoS2-based nanocomposites and their modulated properties in cancer treatment. The review also discussed several therapeutic strategies (photothermal, photodynamic, immunotherapy, gene therapy and chemotherapy) and their combinations for efficient cancer therapy along with certain case studies. The review also inculcates various diagnostic techniques viz. magnetic resonance imaging, computed tomography, photoacoustic imaging and fluorescence imaging for diagnosis of cancer.

引用

页码：257 / 283

页数：27

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