Adjunctive dental therapy via tooth plaque reduction and gingivitis treatment by blue light-emitting diodes tooth brushing

被引:17
|
作者
Genina, Elina A. [1 ,2 ]
Titorenko, Vladimir A. [3 ]
Belikov, Andrey V. [4 ]
Bashkatov, Alexey N. [1 ,2 ]
Tuchin, Valery V. [1 ,2 ,5 ]
机构
[1] Natl Res Saratov State Univ, Opt & Biophoton Dept, Saratov 410012, Russia
[2] Natl Res Tomsk State Univ, Interdisciplinary Lab Biophoton, Tomsk 634050, Russia
[3] Saratov State Med Univ, Fac Dent, Saratov 410012, Russia
[4] St Petersburg Natl Res Univ Informat Technol Mech, Laser Technol & Laser Tech Dept, St Petersburg 197101, Russia
[5] Inst Precise Mech & Control RAS, Saratov 410028, Russia
关键词
phototherapy; tooth brushing; gingivitis; dental plaque; dental devices; home care; RANDOMIZED CLINICAL-TRIAL; PHOTODYNAMIC THERAPY; CHRONIC PERIODONTITIS; VISIBLE-LIGHT; BACTERIA; LASER; PORPHYROMONAS; IRRADIATION;
D O I
10.1117/1.JBO.20.12.128004
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The efficacy of blue light-emitting toothbrushes (B-LETBs) (405 to 420 nm, power density 2 mW/cm(2)) for reduction of dental plaques and gingival inflammation has been evaluated. Microbiological study has shown the multifactor therapeutic action of the B-LETBs on oral pathological microflora: in addition to partial mechanical removal of bacteria, photodynamic action suppresses them up to 97.5%. In the pilot clinical studies, subjects with mild to moderate gingivitis have been randomly divided into two groups: a treatment group that used the BLETBs and a control group that used standard toothbrushes. Indices of plaque, gingival bleeding, and inflammation have been evaluated. A significant improvement of all dental indices in comparison with the baseline (by 59%, 66%, and 82% for plaque, gingival bleeding, and inflammation, respectively) has been found. The treatment group has demonstrated up to 50% improvement relative to the control group. We have proposed the B-LETBs to serve for prevention of gingivitis or as an alternative to conventional antibiotic treatment of this disease due to their effectiveness and the absence of drug side effects and bacterial resistance. (C) 2015 Society of PhotoOptical Instrumentation Engineers (SPIE)
引用
收藏
页数:7
相关论文
共 12 条
  • [1] Photodynamic therapy using light-emitting diodes for the treatment of viral warts
    Ohtsuki, Akiko
    Hasegawa, Toshio
    Hirasawa, Yusuke
    Tsuchihashi, Hitoshi
    Ikeda, Shigaku
    JOURNAL OF DERMATOLOGY, 2009, 36 (10): : 525 - 528
  • [2] Erythrosine as a photosensitizer for antimicrobial photodynamic therapy with blue light-emitting diodes - An in vitro study
    Goncalves, Marcela Leticia Leal
    Santos, Elaine Marcilio
    Renno, Ana Claudia Muniz
    Horliana, Anna Carolina Ratto Tempestini
    Cruz, Matheus de Almeida
    Parisi, Julia Risso
    Prates, Renato Araujo
    Leal-Rossi, Adriana
    Fernandes, Kristianne Porta Santos
    Mesquita-Ferrari, Raquel Agnelli
    Bussadori, Sandra Kalil
    PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2021, 35
  • [3] Coupled blue and red light-emitting diodes therapy efficacy in patients with rosacea: two case reports
    Elisabetta Sorbellini
    Maria Pia De Padova
    Fabio Rinaldi
    Journal of Medical Case Reports, 14
  • [4] Coupled blue and red light-emitting diodes therapy efficacy in patients with rosacea: two case reports
    Sorbellini, Elisabetta
    De Padova, Maria Pia
    Rinaldi, Fabio
    JOURNAL OF MEDICAL CASE REPORTS, 2020, 14 (01)
  • [5] Efficacy of tooth brushing via a three-dimensional motion tracking system for dental plaque control in school children: a randomized controlled clinical trial
    Jin-Sun Jeong
    Kyeong-Seop Kim
    Jeong-Whan Lee
    Kee-Deog Kim
    Wonse Park
    BMC Oral Health, 22
  • [6] Efficacy of tooth brushing via a three-dimensional motion tracking system for dental plaque control in school children: a randomized controlled clinical trial
    Jeong, Jin-Sun
    Kim, Kyeong-Seop
    Lee, Jeong-Whan
    Kim, Kee-Deog
    Park, Wonse
    BMC ORAL HEALTH, 2022, 22 (01)
  • [7] A new tooth brushing approach supported by an innovative hybrid toothbrush-compared reduction of dental plaque after a single use versus an oscillating-rotating powered toothbrush
    D. Klonowicz
    M. Czerwinska
    A. Sirvent
    J-Ph. Gatignol
    BMC Oral Health, 18
  • [8] A new tooth brushing approach supported by an innovative hybrid toothbrush-compared reduction of dental plaque after a single use versus an oscillating-rotating powered toothbrush
    Klonowicz, D.
    Czerwinska, M.
    Sirvent, A.
    Gatignol, J-Ph.
    BMC ORAL HEALTH, 2018, 18
  • [9] Wearable Photomedicine for Neonatal Jaundice Treatment Using Blue Organic Light-Emitting Diodes (OLEDs): Toward Textile-Based Wearable Phototherapeutics
    Choi, Seungyeop
    Jeon, Yongmin
    Kwon, Jeong Hyun
    Ihm, Chunhwa
    Kim, Seung Yeon
    Choi, Kyung Cheol
    ADVANCED SCIENCE, 2022, 9 (35)
  • [10] Topical and Intradermal Efficacy of Photodynamic Therapy with Methylene Blue and Light-Emitting Diode in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis
    Sbeghen, Monica Raquel
    Voltarelli, Evandra Maria
    Campois, Tacito Graminha
    Kimura, Elza
    Alessi Aristides, Sandra Mara
    Hernandes, Luzmarina
    Caetano, Wilker
    Hioka, Noboru
    Valdrinez, Maria
    Lonardoni, Campana
    Verzignassi Silveira, Thais Gomes
    JOURNAL OF LASERS IN MEDICAL SCIENCES, 2015, 6 (03) : 106 - 111