Fungal endophthalmitis caused by Aspergillus ustus in a patient following cataract surgery

被引：26

作者：

Yildiran, Sinasi Taner ^{[1
]}

Mutlu, Fatih Mehmet

Saracli, Mehmet Ali

Uysal, Yusuf

Gonlum, Ahmet

Sobaci, Gungor

Sutton, Deanna A.

机构：

[1] Gulhane Mil Med Acad & Sch Med, Dept Microbiol & Clin Microbiol, Div Med Mycol, TR-06018 Ankara, Turkey

[2] Gulhane Mil Med Acad & Sch Med, Dept Ophthalmol, Div Med Mycol, TR-06018 Ankara, Turkey

[3] Univ Texas, Hlth Sci Ctr, Dept Pathol, Fungus Testing Lab, San Antonio, TX 78229 USA

来源：

MEDICAL MYCOLOGY | 2006年 / 44卷 / 07期

关键词：

Aspergillus ustus; cataract surgery; endophthalmitis;

D O I：

10.1080/13693780600717161

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The first case of postoperative endophthalmitis after cataract surgery caused by Aspergillus ustus, a species that has only rarely been implicated in human disease, is described. Six weeks after cataract surgery, a 67-year-old medically controlled diabetic patient presented with uveitis, mild ciliary injection and ocular discomfort. Anterior chamber paracentesis, vitreous tap and finally complete vitrectomy with removal of the capsular bag including the intraocular lens were performed and several sets of culture yielded A. ustus. Despite vigorous systemic (itraconazole and caspofungin) and intravitreal (amphotericin B and caspofungin) antifungal therapy, the endophthalmitis did not improve. The painful eye with marked inflammation was finally enucleated. In vitro susceptibility testing of the isolate showed that it appeared resistant to amphotericin B, caspofungin, itraconazole, voriconazole, and posaconazole, and susceptible to terbinafine.

引用

页码：665 / 669

页数：5

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