Extremely low frequency alternating magnetic field-triggered and MRI-traced drug delivery by optimized magnetic zeolitic imidazolate framework-90 nanoparticles

被引：66

作者：

Fang, Jie ^{[1
]}

Yang, Yong ^{[1
]}

Xiao, Wen ^{[1
]}

Zheng, Bingwen ^{[2
]}

Lv, Yun-Bo ^{[1
]}

Liu, Xiao-Li ^{[1
]}

Ding, Jun ^{[1
]}

机构：

[1] Natl Univ Singapore, Fac Engn, Dept Mat Sci & Engn, Singapore 117574, Singapore

[2] Natl Univ Singapore, Fac Sci, Dept Chem, Singapore 117543, Singapore

来源：

NANOSCALE | 2016年 / 8卷 / 06期

关键词：

METAL-ORGANIC FRAMEWORKS; HYPERTHERMIA; FUNCTIONALIZATION; RELEASE; ZIF-90; SIZE; CHEMOTHERAPY;

D O I：

10.1039/c5nr08086j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An extremely low frequency alternating magnetic field (ELF-AMF) was demonstrated to be able to effectively trigger drug release from carefully engineered magnetic ZIF-90 nanoparticles. The embedded Fe3O4 nanoparticles or alternatively Gd2O3 nanoparticles serve as effective MRI tracers for potential visualization of drug delivery to ensure drug delivery accuracy.

引用

页码：3259 / 3263

页数：5

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