Eco-friendly, ultrasound-assisted, and facile synthesis of one-pot multicomponent reaction of acridine-1,8(2H,5H)-diones in an aqueous solvent

被引：18
|
作者：
Chavan, Pravin N. [1 ]
Pansare, Dattatraya N. [2 ]
Shelke, Rohini N. [2 ]
机构：
[1] Doshi Vakil Coll, Dept Chem, Goregaon, India
[2] Deogiri Coll, Dept Chem, Stn Rd, Aurangabad 431005, Maharashtra, India
来源：
JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2019年 / 66卷 / 08期
关键词：
ammonium acetate; aqueous solvent; aromatic aldehydes; dimedone; ultrasound irradiation; POTENTIAL ANTITUMOR AGENTS; PYRIMIDINE-DERIVATIVES; MEDIATED SYNTHESIS; ACRIDINE; CATALYST; CYTOTOXICITY; DIACRIDINES; PYRAZOLE;
D O I：
10.1002/jccs.201800411
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-pot, multistep synthesis of acridine-1,8(2H,5H)-diones (4a-m) was achieved by three-component reaction of dimedone (1) with an aromatic aldehyde (2a-m) and an ammonium acetate (3) using water as a green solvent without any catalyst and a simple, easily handled, and ultrasonic technique as well as conventional method.
引用
收藏
页码：822 / 828
页数：7
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