Cu-catalyzed aerobic oxidative C-CN bond cleavage of benzyl cyanide for the synthesis of primary amides

被引：9

作者：

Chen, Xiuling ^{[1
]}

Peng, Yanhong ^{[1
]}

Li, Yan ^{[1
]}

Wu, Minghu ^{[1
]}

Guo, Haibing ^{[1
]}

Wang, Jian ^{[1
]}

Sun, Shaofa ^{[1
]}

机构：

[1] Hubei Univ Sci & Technol, Sch Nucl Technol & Chem & Life Sci, Nonpower Nucl Technol Collaborat Innovat Ctr, Xianning 437100, Peoples R China

来源：

RSC ADVANCES | 2017年 / 7卷 / 30期

基金：

中国国家自然科学基金;

关键词：

ALPHA-HYDROXYPHENYLACETIC ACIDS; PRIMARY ALCOHOLS; PHENYLACETIC ACIDS; CHEMICAL-SYNTHESIS; DIRECT AMIDATION; ALDEHYDES; WATER; EFFICIENT; AMMONIA; KETONES;

D O I：

10.1039/c7ra02207g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient method via copper-catalyzed aerobic oxidative amidation of benzyl cyanide for primary amides is successfully developed. Using readily available NH4Cl as a nitrogen source and Cu/O-2 as a catalytic oxidation system offers new opportunities for C-CN bond cleavage and primary amide bond formation.

引用

页码：18588 / 18591

页数：4

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