Activity-Dependent Plasticity of Spinal Locomotion: Implications for Sensory Processing

被引:39
作者
Edgerton, V. Reggie [1 ,2 ,3 ]
Roy, Roland R. [1 ,3 ]
机构
[1] Univ Calif Los Angeles, Dept Physiol Sci, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Neurobiol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Brain Res Inst, Los Angeles, CA 90095 USA
来源
EXERCISE AND SPORT SCIENCES REVIEWS | 2009年 / 37卷 / 04期
关键词
rehabilitation; epidural stimulation; pharmacological interventions; spinal learning; locomotor training; sensorimotor plasticity; CORD TRANSECTION; RATS; RECOVERY; INJURY; CATS; STEP; SPINALIZATION; CIRCUITRY; CAPACITY;
D O I
10.1097/JES.0b013e3181b7b932
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
EDGERTON, V.R. and R.R. ROY. Activity-dependent Plasticity of spinal locomotion: implications for sensory processing. Exerc. Sport Sci. Rev., Vol. 37, No. 4, Pp. 171-178, 2009. The lumbosacral spinal cord of mammals contains the neural circuitry capable of generating full weight-bearing locomotion of the hind limbs without any supraspinal input. One or more interventions, for example, pharmacological, epidural stimulation, and/or locomotor training, however, are necessary to gain access to and modulate the properties of this circuitry and to facilitate recovery of full weight-bearing locomotion after spinal cord injury.
引用
收藏
页码:171 / 178
页数:8
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