Analysis of Factors for Predicting Survival in Soft-tissue Sarcoma with Metastatic Disease at Initial Presentation

被引：24

作者：

Nakamura, Tomoki ^{[1
]}

Katagiri, Hirohisa ^{[2
]}

Shido, Yoji ^{[3
]}

Hamada, Shunsuke ^{[4
]}

Yamada, Kenji ^{[5
]}

Nagano, Akihito ^{[6
]}

Yamada, Satoshi

Tsukushi, Satoshi ^{[7
,8
]}

Ishimura, Daisuke ^{[9
]}

Matsumine, Akihiko ^{[1
]}

Sudo, Akihiro ^{[1
]}

Nishida, Yoshihiro ^{[4
]}

机构：

[1] Mie Grad Sch Med, Dept Orthopaed Surg, Tsu, Mie, Japan

[2] Sizuoka Canc Hosp, Div Orthopaed Oncol, Nagaizumi, Shizuoka, Japan

[3] Hamamatsu Med Univ, Dept Orthopaed Surg, Hamamatsu, Shizuoka, Japan

[4] Nagoya Univ, Grad Sch Med, Dept Orthopaed Surg, Nagoya, Aichi, Japan

[5] Aichi Hosp, Aichi Canc Ctr, Dept Orthoped Surg, Okazaki, Aichi, Japan

[6] Gifu Univ, Grad Sch Med, Dept Orthoped Surg, Gifu, Japan

[7] Nagoya City Univ, Grad Sch Med Sci, Dept Orthoped Surg, Nagoya, Aichi, Japan

[8] Aichi Canc Ctr, Dept Orthopaed Surg, Nagoya, Aichi, Japan

[9] Fujita Hlth Univ, Sch Med, Dept Orthopaed Surg, Toyoake, Aichi, Japan

来源：

ANTICANCER RESEARCH | 2017年 / 37卷 / 06期

关键词：

Soft tissue sarcoma; C-reactive protein; albumin; metastasis; C-REACTIVE PROTEIN; SYSTEMIC INFLAMMATORY MARKERS; GLASGOW PROGNOSTIC SCORE; CLINICAL-SIGNIFICANCE; CARCINOMA; CANCER; LEVEL; RATIO;

D O I：

10.21873/anticanres.11671

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background/Aim: We aimed to confirm predictors of survival in soft-tissue sarcoma (STS) patients with metastatic disease at initial presentation in 9 Institutions under the Tokai Musculoskeletal Oncology Consortium. Patients and Methods: Between 2008 and 2013, 47 STS patients with metastatic disease at initial presentation were referred for treatment. The mean follow-up duration was 24 months. Results: The mean C-reactive protein (CRP) levels were 2.47 mg/dl. The mean hemoglobin and albumin levels were 13.1 g/dl and 4.1 g/dl, respectively. Hemoglobin and albumin levels were significantly correlated with CRP levels. In the multivariate analysis, age, CRP levels, and albumin levels were confirmed as independent prognostic factors for disease-specific survival (DSS). Conclusion: We suggest that the measurements of CRP and albumin levels are a useful method of identifying STS patients with metastasis at initial presentation that have poor prognosis.

引用

页码：3137 / 3141

页数：5

共 18 条

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