Decreased major histocompatibility complex class II expression in diffuse large B-cell lymphoma does not correlate with CpG methylation of class II transactivator promoters III and IV

被引：8

作者：

Wilkinson, Sarah T. ^{[1
]}

Fernandez, Diane R. ^{[1
]}

Murphy, Shawn P. ^{[2
]}

Braziel, Rita M. ^{[3
]}

Campo, Elias ^{[4
]}

Chan, Wing C. ^{[5
]}

Delabie, Jan ^{[6
]}

Gascoyne, Randy D. ^{[7
]}

Staudt, Louis M. ^{[8
]}

Jaffe, Elaine S. ^{[9
]}

Rosenwald, Andreas ^{[10
]}

Rimsza, Lisa M. ^{[1
]}

机构：

[1] Univ Arizona, Dept Pathol, Tucson, AZ 85724 USA

[2] Univ Rochester, Sch Med & Dent, Dept Obstet & Gynecol, Rochester, NY 14642 USA

[3] Oregon Hlth & Sci Univ, Dept Pathol, Portland, OR 97201 USA

[4] Univ Barcelona, Dept Pathol, Hosp Clin, Barcelona, Spain

[5] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE USA

[6] Radium Hosp, Dept Pathol, Oslo, Norway

[7] British Columbia Canc Agcy, Dept Pathol, Vancouver, BC V5Z 4E6, Canada

[8] NCI, Metab Branch, Pathol Lab, Ctr Canc Res, Bethesda, MD 20892 USA

[9] NCI, Hematopathol Sect, Pathol Lab, Ctr Canc Res, Bethesda, MD 20892 USA

[10] Univ Wurzburg, Inst Pathol, D-8700 Wurzburg, Germany

来源：

LEUKEMIA & LYMPHOMA | 2009年 / 50卷 / 11期

关键词：

POOR PATIENT SURVIVAL; PROTEIN EXPRESSION; CIITA; GENE; MECHANISM; GAMMA;

D O I：

10.3109/10428190903297531

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1875 / U187

页数：5

共 15 条

[1] HUMAN B-CELL VARIANTS IMMUNOSELECTED AGAINST A SINGLE IA-ANTIGEN SUBSET HAVE LOST EXPRESSION OF SEVERAL IA-ANTIGEN SUBSETS [J].

ACCOLLA, RS .

JOURNAL OF EXPERIMENTAL MEDICINE, 1983, 157 (03) :1053-1058

[2] Alterations in CIITA constitute a common mechanism accounting for downregulation of MHC class II expression in diffuse large B-cell lymphoma (DLBCL) [J].

Cycon, Kell A. ;

Rimsza, Lisa M. ;

Murphy, Shawn P. .

EXPERIMENTAL HEMATOLOGY, 2009, 37 (02) :184-194

[3] A GENOMIC SEQUENCING PROTOCOL THAT YIELDS A POSITIVE DISPLAY OF 5-METHYLCYTOSINE RESIDUES IN INDIVIDUAL DNA STRANDS [J].

FROMMER, M ;

MCDONALD, LE ;

MILLAR, DS ;

COLLIS, CM ;

WATT, F ;

GRIGG, GW ;

MOLLOY, PL ;

PAUL, CL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (05) :1827-1831

[4] Inactivation of class II transactivator by DNA methylation and histone deacetylation associated with absence of HLA-DR induction by interferon-γ in haematopoietic tumour cells [J].

Morimoto, Y ;

Toyota, M ;

Satoh, A ;

Murai, M ;

Mita, H ;

Suzuki, H ;

Takamura, Y ;

Ikeda, H ;

Ishida, T ;

Sato, N ;

Tokino, T ;

Imai, K .

BRITISH JOURNAL OF CANCER, 2004, 90 (04) :844-852

[5] Kinetics of a gamma interferon response: Expression and assembly of CIITA promoter IV and inhibition by methylation [J].

Morris, AC ;

Beresford, GW ;

Mooney, MR ;

Boss, JM .

MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (13) :4781-4791

[6] Methylation of class II trans-activator promoter IV:: A novel mechanism of MHC class II gene control [J].

Morris, AC ;

Spangler, WE ;

Boss, JM .

JOURNAL OF IMMUNOLOGY, 2000, 164 (08) :4143-4149

[7] Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA [J].

MuhlethalerMOttet, A ;

Otten, LA ;

Steimle, V ;

Mach, B .

EMBO JOURNAL, 1997, 16 (10) :2851-2860

[8] Gene expression predicts overall survival in paraffin-embedded tissues of diffuse large B-cell lymphoma treated with R-CHOP [J].

Rimsza, Lisa M. ;

LeBlanc, Michael L. ;

Unger, Joseph M. ;

Miller, Thomas P. ;

Grogan, Thomas M. ;

Persky, Daniel O. ;

Martel, Ralph R. ;

Sabalos, Constantine M. ;

Seligmann, Bruce ;

Braziel, Rita M. ;

Campo, Elias ;

Rosenwald, Andreas ;

Connors, Joseph M. ;

Sehn, Laurie H. ;

Johnson, Nathalie ;

Gascoyne, Randy D. .

BLOOD, 2008, 112 (08) :3425-3433

[9] CIITA or RFX coding region loss of function mutations occur rarely in diffuse large B-cell lymphoma cases and cell lines with low levels of major histocompatibility complex class II expression [J].

Rimsza, Lisa M. ;

Chan, Wing C. ;

Gascoyne, Randy D. ;

Campo, Elias ;

Jaffe, Elaine S. ;

Staudt, Louis M. ;

Delabie, Jan ;

Rosenwald, Andreas ;

Murphy, Shawn P. .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (04) :596-598

[10] Loss of major histocompatibility class II expression in non-immune-privileged site diffuse large B-cell lymphoma is highly coordinated and not due to chromosomal deletions [J].

Rimsza, LM ;

Roberts, RA ;

Campo, E ;

Grogan, TM ;

Bea, S ;

Salaverria, I ;

Zettl, A ;

Rosenwald, A ;

Ott, G ;

Muller-Hermelink, HK ;

Delabie, J ;

Fisher, RI ;

Unger, JM ;

LeBlanc, M ;

Staudt, LM ;

Jaffe, ES ;

Gascoyne, RD ;

Chan, WC ;

Weisenburger, DD ;

Greiner, T ;

Braziel, RM ;

Miller, TP .

BLOOD, 2006, 107 (03) :1101-1107

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