Osteosarcoma in a pregnant patient with McCune-Albright syndrome

被引：20

作者：

Kanazawa, Ippei ^{[1
]}

Yamauchi, Mika ^{[1
]}

Yano, Shozo ^{[1
]}

Imanishi, Yasuo ^{[2
]}

Kitazawa, Riko ^{[3
]}

Nariai, Yoshiki ^{[4
]}

Araki, Asuka ^{[5
]}

Kobayashi, Keisuke ^{[2
]}

Inaba, Masaaki ^{[2
]}

Maruyama, Riruke ^{[6
]}

Yamaguchi, Toru ^{[1
]}

Sugimoto, Toshitsugu ^{[1
]}

机构：

[1] Shimane Univ, Fac Med, Dept Internal Med 1, Izumo, Shimane 6938501, Japan

[2] Osaka City Univ, Grad Sch Med, Dept Metab Endocrinol & Mol Med, Osaka, Japan

[3] Kobe Univ, Grad Sch Med, Dept Pathol, Div Pathol, Kobe, Hyogo, Japan

[4] Shimane Univ, Dept Oral & Maxillofacial Surg, Fac Med, Matsue, Shimane, Japan

[5] Shimane Univ, Dept Pathol, Fac Med, Organ Pathol Unit, Matsue, Shimane, Japan

[6] Shimane Univ, Pathol Lab, Fac Med, Matsue, Shimane, Japan

来源：

BONE | 2009年 / 45卷 / 03期

关键词：

Osteosarcoma; McCune-Albright syndrome; Pregnant; Acromegaly; GROWTH-FACTOR-I; HORMONE-RELATED PROTEIN; STIMULATORY G-PROTEIN; FIBROUS-DYSPLASIA; C-FOS; MALIGNANT TRANSFORMATION; CELL-LINES; BONE; RECEPTOR; EXPRESSION;

D O I：

10.1016/j.bone.2009.05.018

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Malignant transformation of fibrous dysplasia is very rare and has not been previously described in patients with McCune-Albright syndrome in the absence of radiation treatment during gestation. Here, we report a 38-year-old pregnant woman with McCune-Albright syndrome and acromegaly accompanied by osteosarcoma. The patient was in the 6th week of pregnancy, when she visited our hospital. She had Multiple fibrous dysplasia, skin pigmentation, and acromegaly. The markedly high bone turnover rate during pregnancy tended to decrease after a normal delivery. Fibrous dysplasia of the lower jaw rapidly increased in the 37th week of pregnancy, and the tumor was surgically resected after delivery. Pathological examination of the resected tumor revealed fibrous dysplasia admixed with osteosarcoma containing chondroblastic and osteoblastic tissue. We firstly reported a case of osteosarcoma in a patient with McCune-Albright syndrome, which rapidly progressed during pregnancy. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：603 / 608

页数：6

共 50 条

[1] Osteosarcoma in a patient with McCune-Albright syndrome and Mazabrand's syndrome
Lopez-Ben, R
Pitt, MJ
Jaffe, KA
Siegal, GP
SKELETAL RADIOLOGY, 1999, 28 (09) : 522 - 526
[2] Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud’s syndrome
R. Lopez-Ben
Michael J. Pitt
Kenneth A. Jaffe
Gene P. Siegal
Skeletal Radiology, 1999, 28 : 522 - 526
[3] Breast cancer in a patient with McCune-Albright syndrome
Tanabe Y.
Nakahara S.
Mitsuyama S.
Ono M.
Toyoshima S.
Breast Cancer, 1998, 5 (2) : 175 - 178
[4] Sarcomatous transformation in the McCune-Albright syndrome
Machado Pires de Araujo, Pedro Ivo
Rocha Soares, Vitor Yamashiro
Queiroz, Andre Luis
dos Santos, Aline Marques
Nascimento, Luiz Augusto
ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG, 2012, 16 (02): : 217 - 220
[5] Acromegaly and McCune-Albright Syndrome
Salenave, Sylvie
Boyce, Alison M.
Collins, Michael T.
Chanson, Philippe
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (06) : 1955 - 1969
[6] Sarcomatous transformation in the McCune-Albright syndrome
Pedro Ivo Machado Pires de Araújo
Vítor Yamashiro Rocha Soares
André Luís Queiroz
Aline Marques dos Santos
Luiz Augusto Nascimento
Oral and Maxillofacial Surgery, 2012, 16 (2) : 217 - 220
[7] Thyroid Abnormalities in Children and Adolescents with McCune-Albright Syndrome
Tessaris, D.
Corrias, A.
Matarazzo, P.
De Sanctis, L.
Wasniewska, M.
Messina, M. F.
Vigone, M. C.
Lala, R.
HORMONE RESEARCH IN PAEDIATRICS, 2012, 78 (03): : 151 - 157
[8] McCune-Albright syndrome
Claudia E Dumitrescu
Michael T Collins
Orphanet Journal of Rare Diseases, 3
[9] Cushing Syndrome in the McCune-Albright Syndrome
Brown, Rebecca J.
Kelly, Marilyn H.
Collins, Michael T.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (04) : 1508 - 1515
[10] A Rare Case of Headache in a Patient With McCune-Albright Syndrome: A Triple Threat
Shah, Ravi
Das, Liza
Dutta, Pinaki
Sood, Ashwani
Bhadada, Sanjay Kumar
CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (09)

← 1 2 3 4 5 →