Feasibility and Acceptability of an Alcohol Addiction Therapy Integrated in a Transplant Center for Patients Awaiting Liver TransplantationaEuro

被引：19

作者：

Erim, Yesim ^{[1
]}

Boettcher, Michael ^{[2
]}

Schieber, Katharina ^{[1
]}

Lindner, Marion ^{[3
]}

Klein, Christian ^{[4
]}

Paul, Andreas ^{[4
]}

Beckebaum, Susanne ^{[5
]}

Mayr, Andreas ^{[6
]}

Helander, Anders ^{[7
,8
]}

机构：

[1] Univ Hosp Erlangen, Dept Psychosomat & Psychotherapeut Med, Erlangen, Germany

[2] MVZ Lab Dessau GmbH, Dessau Rosslau, Germany

[3] Univ Hosp Essen, Dept Psychosomat & Psychotherapeut Med, Essen, Germany

[4] Univ Hosp Essen, Dept Gen Visceral & Transplantat Surg, Essen, Germany

[5] Univ Hosp Munster, Dept Transplant Med, Munster, Germany

[6] Univ Erlangen Nurnberg, Dept Med Informat Biometry & Epidemiol, D-91054 Erlangen, Germany

[7] Karolinska Inst, Dept Lab Med, Stockholm, Sweden

[8] Karolinska Univ Lab, Stockholm, Sweden

来源：

ALCOHOL AND ALCOHOLISM | 2016年 / 51卷 / 01期

关键词：

URINARY ETHYL GLUCURONIDE; LONG-TERM SURVIVAL; CIRRHOSIS; CONSUMPTION; DISEASE; RELAPSE; PREDICTORS; ABSTINENCE;

D O I：

10.1093/alcalc/agv075

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

To evaluate the feasibility and acceptability of an addiction program within the setting of liver transplantation, with classification of behavior change techniques used to reduce excessive drinking. Patients with alcohol-related liver disease (N = 100) participated in a manualized addiction group therapy over 12 sessions, pre-transplantation. Relapses were identified by measurement of urinary ethyl glucuronide (EtG). Two groups were identified according to the frequency of participation: completers (n = 42) vs. drop-outs (n = 58). A total of 16.5% of the samples of completers in comparison to 30.5% of the samples of drop-outs tested positive for EtG (P < 0.001). The results suggest that implementation of an addiction therapy program during the waiting time might help to limit the frequency of drinking. These patients appeared often to under-report their alcohol consumption; including a biomarker such as urinary EtG in such settings is recommended.

引用

页码：40 / 46

页数：7

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