Are Modic Changes Associated With Health-related Quality of Life After Discectomy A Study on 620 Patients With Two-year Follow-up

被引:12
作者
Udby, Peter Muhareb [1 ,2 ,3 ]
Ohrt-Nissen, Soren [4 ]
Bendix, Tom [2 ]
Paulsen, Rune [3 ]
Stottrup, Christian [3 ]
Andresen, Andreas [3 ]
Brorson, Stig [1 ]
Carreon, Leah Y. [3 ]
Andersen, Mikkel Osterheden [3 ]
机构
[1] Zealand Univ Hosp, Dept Orthoped Surg, Spine Unit, Koge, Denmark
[2] Univ Copenhagen, Rigshosp, Ctr Rheumatol & Spine Dis, Copenhagen, Denmark
[3] Spine Ctr Southern Denmark, Spine Surg & Res, Odense, Denmark
[4] Univ Copenhagen, Rigshosp, Dept Orthopaed Surg, Spine Unit, Copenhagen, Denmark
关键词
back pain; disc degeneration; herniated lumbar disc; LBP; long-term follow-up; Modic changes; spine;
D O I
10.1097/BRS.0000000000003618
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Study Design. A registry-based comparative cohort study with 2-year follow-up. Objective. To assess whether Modic changes (MCs) are associated with health-related quality of life, long-term physical disability, back- or leg pain after discectomy. Summary of Background Data. Previous studies have failed to show a clinically significant association between MCs and patient-reported outcomes (PROs) after discectomy. Methods. Data from the Danish National Spine Registry on patients undergoing first-time lumbar discectomy at a single institution from 2014 to 2017 with an accessible preoperative lumbar magnetic resonance imaging, complete preoperative, and 2-year follow-up questionnaires were obtained. PROs including Oswestry disability index (ODI), European Quality of Life-Five Dimensions (EQ-5D), visual analogue scale (VAS) back and leg pain, and patient satisfaction were collected. Patients were stratified based on the presence (+MC) or absence (-MC) of MCs on the preoperative MRI. Results. Of 620 patients included, MCs were present in 290 patients (47%). Of these, MC type 1 (MC-1) was present in 73 (25%) and MC type 2 (MC-2) in 217 (75%) patients. Preoperative data for ODI, EQ-5D, VAS-BP, and VAS-LP were comparable for the +MC and -MC groups. Both groups had a statistically significant improvement in PROs from baseline compared with 2-year follow-up (P < 0.001). At 2-year follow-up, both groups had improved with no significant difference between them in regards to ODI (15.5 vs. 17.2, P = 0.208); EQ-5D (0.75 vs. 0.72, P = 0.167); VAS-BP (27.1 vs. 28.3, P = 0.617); VAS-LP (26.8 vs. 25.0, P = 0.446); and patient satisfaction (74% vs. 76%, P = 0.878). Conclusion. MCs were not found to be associated with health-related quality of life, disability, back- or leg pain, or patient satisfaction 2 years after discectomy.
引用
收藏
页码:1491 / 1497
页数:7
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