Correlation analysis of candidate gene SNP for high-yield in Liaoning cashmere goats with litter size and cashmere performance

被引：2
作者：
Yue, Chang [1 ]
Bai, Wen L. [1 ]
Zheng, Yuan Y. [1 ]
Hui, Tai Y. [1 ]
Sun, Jia M. [1 ]
Guo, Dan [2 ]
Guo, Su L. [3 ]
Wang, Ze Y. [1 ]
机构：
[1] Shenyang Agr Univ, Coll Anim Husb & Vet Med, 120 Dongling Rd, Shenyang 110866, Liaoning, Peoples R China
[2] Anim Sci Res Inst Liaoning Prov, Liaoyang, Peoples R China
[3] Prosperous Community, Changshun Town, Huade, Peoples R China
来源：
ANIMAL BIOTECHNOLOGY | 2021年 / 32卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Cashmere goat; high-yield gene; single nucleotide polymorphism (SNP); litter size; cashmere fineness; SINGLE NUCLEOTIDE POLYMORPHISMS; OVULATION RATE; FECUNDITY GENES; GROWTH TRAITS; GDF9; GENE; BMP RECEPTORS; FECB GENE; HAN SHEEP; ASSOCIATION; MUTATION;
D O I：
10.1080/10495398.2019.1652188
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
This study was designed to identify the relationship of four genes (GDF9, BMPR-IB, FecB and ESR) polymorphisms in the 3 ' UTR region with litter size and cashmere performance of Liaoning cashmere goats (LCG, n = 1140). The ESR C463T and T575G loci of LCG were genotyped. The results of correlation analysis showed that five effective single nucleotide polymorphisms (SNPs) loci (C47T, C94T, C299T, C463T and T575G) were found in the four genes. The lambing number of CC and CT genotypic individuals at FecB C94T locus was significantly higher than that of TT genotypic individuals (45.7 and 46.8%, respectively); the lambing number of CC genotypic individuals at ESR C463T locus was significantly higher than that of CT, TT genotypic individuals (9 and 15%, respectively); There was a positive correlation between CC genotype at C463T locus and cashmere fineness. In this study, the relationship between FecB C94T and ESR C463T loci C alleles and lambing number in LCG was preliminarily revealed. These results further confirmed that FecB and ESR genes may be significantly correlated with high fecundity of LCG.
引用
收藏
页码：43 / 50
页数：8
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