Effect of reduced mu opioid receptor density on the relative efficacy of full and partial agonists for G-protein activation.

被引：0
|
作者：
Rorrer, WK [1 ]
Selley, DE [1 ]
机构：
[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Pharmacol & Toxicol, Richmond, VA 23298 USA
来源：
FASEB JOURNAL | 2000年 / 14卷 / 08期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
405
引用
收藏
页码：A1380 / A1380
页数：1
相关论文
共 50 条
  • [1] Comparison of G-protein activation in the brain by μ-, δ-, and κ-opioid receptor agonists in μ-opioid receptor knockout mice
    Park, Y
    Ma, T
    Tanaka, S
    Jang, CG
    Loh, HH
    Ko, KH
    Ho, IK
    BRAIN RESEARCH BULLETIN, 2000, 52 (04) : 297 - 302
  • [2] Down-regulation of mu-opioid receptor by full but not partial agonists is independent of G protein coupling
    Yabaluri, N
    Medzihradsky, F
    MOLECULAR PHARMACOLOGY, 1997, 52 (05) : 896 - 902
  • [3] Absence of G-protein activation by μ-opioid receptor agonists in the spinal cord of μ-opioid receptor knockout mice
    Narita, M
    Mizoguchi, H
    Narita, M
    Sora, I
    Uhl, GR
    Tseng, LF
    BRITISH JOURNAL OF PHARMACOLOGY, 1999, 126 (02) : 451 - 456
  • [4] The effect of sodium ion on μ-opioid receptor G-protein activation
    Ferenc Zador
    Sandor Benyhe
    PHARMACOLOGICAL REPORTS, 2011, 63 (01) : 235 - 236
  • [5] Region-dependent G-protein activation by κ-opioid receptor agonists in the mouse brain
    Mizoguchi, H
    Leitermann, RJ
    Narita, M
    Nagase, H
    Suzuki, T
    Tseng, LF
    NEUROSCIENCE LETTERS, 2004, 356 (02) : 145 - 147
  • [6] G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists
    Stahl, Edward L.
    Schmid, Cullen L.
    Acevedo-Canabal, Agnes
    Read, Cai
    Grim, Travis W.
    Kennedy, Nicole M.
    Bannister, Thomas D.
    Bohn, Laura M.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (48)
  • [7] Efficacy of heroin metabolites for G-protein activation by the delta opioid receptor.
    Selley, DE
    Wojno, H
    May, EL
    FASEB JOURNAL, 2000, 14 (08): : A1380 - A1380
  • [8] Agonists determine the pattern of G-protein activation in μ-opioid receptor-mediated supraspinal analgesia
    Sánchez-Blázquez, P
    Gómez-Serranillos, P
    Garzón, J
    BRAIN RESEARCH BULLETIN, 2001, 54 (02) : 229 - 235
  • [9] Increased MU-opioid receptor mediated G-protein activation in mice with diabetes mellitus
    Cheng, EY
    Pham, NM
    Mizoguchi, H
    Narita, M
    Tseng, LF
    ANESTHESIOLOGY, 1999, : U12 - U12
  • [10] Increase mu-opioid receptor mediate G-protein activation in mice with diabetes mellitus
    Chng, EY
    Phan, NM
    Mizoguchi, H
    Narita, M
    Tseng, LF
    ANESTHESIOLOGY, 1999, 91 (3A) : U380 - U380
12345