Synthesis of cationic porphyrin modified amino acids

被引：28

作者：

Biron, E

Voyer, N ^{[1
]}

机构：

[1] Univ Laval, Fac Sci & Genie, Dept Chim, Ste Foy, PQ G1K 7P4, Canada

[2] Univ Laval, Fac Sci & Genie, CREFSIP, Ste Foy, PQ G1K 7P4, Canada

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 37期

关键词：

D O I：

10.1039/b508380j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Derivatives of amino acids bearing a porphyrin moiety on a side chain were synthesized by coupling a porphyrin to a glutamic acid side chain; the utility of these compounds was demonstrated by their use in solid-phase synthesis of a peptide bearing a cationic porphyrin and by studying its DNA-binding properties.

引用

收藏

页码：4652 / 4654

页数：3

相关论文

共 38 条

[1]

Ackroyd R, 2001, PHOTOCHEM PHOTOBIOL, V74, P656, DOI 10.1562/0031-8655(2001)074<0656:THOPAP>2.0.CO

[2]

2

[3] A SIMPLIFIED SYNTHESIS FOR MESO-TETRAPHENYLPORPHIN [J].

ADLER, AD ;

LONGO, FR ;

FINARELLI, JD ;

GOLDMACH.J ;

ASSOUR, J ;

KORSAKOF.L .

JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (02) :476-+

[4] COMPARISON OF THE EFFECTS OF CATIONIC PORPHYRINS ON DNA PROPERTIES - INFLUENCE OF GC CONTENT OF NATIVE AND SYNTHETIC-POLYMERS [J].

BANVILLE, DL ;

MARZILLI, LG ;

STRICKLAND, JA ;

WILSON, WD .

BIOPOLYMERS, 1986, 25 (10) :1837-1858

[5] INTERCALATIVE AND NONINTERCALATIVE BINDING OF LARGE CATIONIC PORPHYRIN LIGANDS TO POLYNUCLEOTIDES [J].

CARVLIN, MJ ;

MARK, E ;

FIEL, R ;

HOWARD, JC .

NUCLEIC ACIDS RESEARCH, 1983, 11 (17) :6141-6154

[6] Current clinical and preclinical photosensitizers for use in photodynamic therapy [J].

Detty, MR ;

Gibson, SL ;

Wagner, SJ .

JOURNAL OF MEDICINAL CHEMISTRY, 2004, 47 (16) :3897-3915

[7]

DING L, 1990, NEW J CHEM, V14, P421

[8] Porphyrin derivatives for telomere binding and telomerase inhibition [J].

Dixon, IM ;

Lopez, F ;

Estève, JP ;

Tejera, AM ;

Blasco, MA ;

Pratviel, G ;

Meunier, B .

CHEMBIOCHEM, 2005, 6 (01) :123-132

[9] ELECTRON-SPIN-RESONANCE SPECTROSCOPIC AND SPECTROPHOTOMETRIC INVESTIGATION OF THE BINDING OF TETRACATIONIC PORPHYRINS AND PORPHYRAZINES WITH CALF THYMUS DNA - UNEQUIVOCAL EVIDENCE FOR INTERCALATION [J].

DOUGHERTY, G ;

PILBROW, JR ;

SKOROBOGATY, A ;

SMITH, TD .

JOURNAL OF THE CHEMICAL SOCIETY-FARADAY TRANSACTIONS II, 1985, 81 :1739-1759

[10] INTERACTION OF DNA WITH A PORPHYRIN LIGAND - EVIDENCE FOR INTERCALATION [J].

FIEL, RJ ;

HOWARD, JC ;

MARK, EH ;

DATTAGUPTA, N .

NUCLEIC ACIDS RESEARCH, 1979, 6 (09) :3093-3118

← 1 2 3 4 →