Coagulation diagnostics and treatment for recurrent pregnancy loss and implantation failure

被引：0

作者：

Rogenhofer, Nina ^{[1
]}

Bohlmann, Michael K. ^{[2
]}

机构：

[1] LMU Munchen, Klin & Poliklin Frauenheilkunde & Geburtshilfe, Munich, Germany

[2] St Elisabethen Krankenhaus Lorrach, Frauenklin, Feldbergstr 15, D-79539 Lorrach, Germany

来源：

GYNAKOLOGISCHE ENDOKRINOLOGIE | 2019年 / 17卷 / 03期

关键词：

Coagulation disorders; Anticoagulants; Heparin; Aspirin; Thrombophilia; MOLECULAR-WEIGHT HEPARIN; THROMBOPHILIC GENE-MUTATIONS; VENOUS THROMBOEMBOLISM; RISK-FACTORS; WOMEN; MULTICENTER; MISCARRIAGE; PREVENTION; DISORDERS; HAPLOTYPE;

D O I：

10.1007/s10304-019-0261-z

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recurrent spontaneous abortions (RSA) affect 1%-3% of all couples. In addition to genetic, endocrine, anatomical, autoimmune and infectious causes, maternal thrombophilia has been discussed as a risk factor for this disease. Like RSA, recurrent implantation failure (RIF) is understood as a constellation in which no pregnancy occurs after several embryo transfers in the course of multiple in vitro fertilization and intracytoplasmic sperm injection (IVF/ICSI) cycles. RIF has also been attributed to maternal thrombophilia. This review article summarizes the current data on diagnosis and treatment of both diseases with regard to maternal thrombophilia.

引用

页码：148 / 153

页数：6

共 52 条

[1] Definitions of infertility and recurrent pregnancy loss [J].

不详 .

FERTILITY AND STERILITY, 2008, 89 (06) :1603-1603

[2]

[Anonymous], 2013, OBSTET GYNECOL

[3]

[Anonymous], 2011, INV TREATM COUPL REC

[4]

[Anonymous], 2017, RECURRENT PREGNANCY LOSS Guideline of the European Society of Human Reproduction and Embryology

[5]

[Anonymous], 2002, INT J GYNAECOL OBSTE, DOI DOI 10.1016/S0020-7292(02)00197-2

[6] Thrombophilia and assisted reproduction technology-any detrimental impact or unnecessary overuse? [J].

Ata, Baris ;

Urman, Bulent .

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2016, 33 (10) :1305-1310

[7] Recurrent Implantation Failure-update overview on etiology, diagnosis, treatment and future directions [J].

Bashiri, Asher ;

Halper, Katherine Ida ;

Orvieto, Raoul .

REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2018, 16

[8] VTE, Thrombophilia, Antithrombotic Therapy, and Pregnancy Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines [J].

Bates, Shannon M. ;

Greer, Ian A. ;

Middeldorp, Saskia ;

Veenstra, David L. ;

Prabulos, Anne-Marie ;

Vandvik, Per Olav .

CHEST, 2012, 141 (02) :E691S-E736S

[9] Risk stratification and heparin prophylaxis to prevent venous thromboembolism in pregnant women [J].

Bauersachs, Rupert M. ;

Dudenhausen, Joachim ;

Faridi, Andree ;

Fischer, Thorsten ;

Fung, Samson ;

Geisen, Ulrich ;

Harenberg, Job ;

Herchenhan, Eberhard ;

Keller, Franz ;

Kemkes-Matthes, Bettina ;

Schinzel, Helmut ;

Spannagl, Michael ;

Thaler, Christian J. .

THROMBOSIS AND HAEMOSTASIS, 2007, 98 (06) :1237-1245

[10] Maternal Factor V Leiden and Prothrombin Mutations Do Not Seem to Contribute to the Occurrence of Two or More Than Two Consecutive Miscarriages in Caucasian patients [J].

Baumann, Kristin ;

Beuter-Winkler, Petra ;

Hackethal, Andreas ;

Strowitzki, Thomas ;

Toth, Bettina ;

Bohlmann, Michael K. .

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2013, 70 (06) :518-521

← 1 2 3 4 5 6 →