The role of phosphorylation at Y125 in regulating the structure, aggregation, and membrane binding of alpha-synuclein: Implications for the pathogenesis of Parkinson's disease

被引:0
|
作者
Hejjaoui, Mirva [1 ]
Butterfield, Sara [1 ]
Fauvet, Bruno [1 ]
Prudent, Michel [1 ]
Olscheswki, Diana [1 ]
Eliezer, David [1 ]
Lashuel, Hilal [1 ]
机构
[1] Weill Cornell Med Coll, New York, NY USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:524 / 524
页数:1
相关论文
共 50 条
  • [1] Phosphorylation of α-Synuclein at Y125 and S129 Alters Its Metal Binding Properties: Implications for Understanding the Role of α-Synuclein in the Pathogenesis of Parkinson's Disease and Related Disorders
    Lu, Yu
    Prudent, Michel
    Fauvet, Bruno
    Lashuel, Hilal A.
    Girault, Hubert H.
    ACS CHEMICAL NEUROSCIENCE, 2011, 2 (11): : 667 - 675
  • [2] Alpha-Synuclein Aggregation in Parkinson's Disease
    Srinivasan, E.
    Chandrasekhar, G.
    Chandrasekar, P.
    Anbarasu, K.
    Vickram, A. S.
    Karunakaran, Rohini
    Rajasekaran, R.
    Srikumar, P. S.
    FRONTIERS IN MEDICINE, 2021, 8
  • [3] Sumoylation of alpha-synuclein in the pathogenesis of parkinson's disease
    Engelender, S.
    JOURNAL OF NEUROCHEMISTRY, 2019, 150 : 48 - 48
  • [4] Lipids and alpha-synuclein aggregation in Parkinson's disease
    Broersen, K.
    Davletov, B.
    MOVEMENT DISORDERS, 2007, 22 (12) : VI - VI
  • [5] Role of Alpha-Synuclein in Parkinson's Disease
    Link, Tina
    Maraghi, Sophie
    Reddy, Megan
    Sheth, Heli
    Stark, Kaylan
    Vijay, Varun
    FASEB JOURNAL, 2021, 35
  • [6] The Role of Lipid Chemistry in Alpha-Synuclein Membrane Binding and Aggregation
    Rocha, Sandra
    Wittung-Stafshede, Pernilla
    BIOPHYSICAL JOURNAL, 2018, 114 (03) : 277A - 277A
  • [7] Role of post-translational modifications on the alpha-synuclein aggregation-related pathogenesis of Parkinson's disease
    Yoo, Hajung
    Lee, Jeongmin
    Kim, Bokwang
    Moon, Heechang
    Jeong, Huisu
    Lee, Kyungmi
    Song, Woo Jeung
    Hur, Junho K.
    Oh, Yohan
    BMB REPORTS, 2022, 55 (07) : 323 - 335
  • [8] Calpain in the cleavage of alpha-synuclein and the pathogenesis of Parkinson's disease
    Shams, Ramsha
    Banik, Naren L.
    Haque, Azizul
    MOLECULAR BASIS OF NEUROPSYCHIATRIC DISORDERS: FROM BENCH TO BEDSIDE, 2019, 167 : 107 - 124
  • [9] Triggers of alpha-synuclein aggregation and inhibition in Parkinson's disease
    Baum, Jean
    Janowska, Maria
    Olson, Michael
    Atieh, Tamr
    Nunes, Ana Monica
    Moriarty, Gina
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 252
  • [10] The interplay between parkin and alpha-synuclein; possible implications for the pathogenesis of Parkinson's disease
    Jesko, Henryk
    Lenkiewicz, Anna M.
    Wilkaniec, Anna
    Adamczyk, Agata
    ACTA NEUROBIOLOGIAE EXPERIMENTALIS, 2019, 79 (03) : 276 - 289