Lipid-Modulated Pharmacophore Nanorods Assembled at the Air/Water Interface

被引：3
|
作者：
Philosof-Mazor, Liron [2 ,3 ]
Volinsky, Roman [2 ,3 ]
Jopp, Jurgen [2 ,3 ]
Blumberg, Peter [4 ]
Rapaport, Hanna [5 ]
Marquez, Victor E. [1 ]
Jelinek, Raz [2 ,3 ]
机构：
[1] NCI, Med Chem Lab, Ctr Canc Res, NIH, Frederick, MD 21702 USA
[2] Ben Gurion Univ Negev, Dept Chem, IL-84105 Beer Sheva, Israel
[3] Ben Gurion Univ Negev, Ilse Katz Inst Nanotechnol, IL-84105 Beer Sheva, Israel
[4] NCI, Lab Canc Biol & Genet, Ctr Canc Res, NIH, Bethesda, MD 20992 USA
[5] Ben Gurion Univ Negev, Dept Biotechnol Engn, IL-84105 Beer Sheva, Israel
来源：
CHEMPHYSCHEM | 2009年 / 10卷 / 15期
基金：
美国国家卫生研究院;
关键词：
biomimetic chemistry; DAG lactones; Langmuir-Blodgett films; monolayers; nanostructures; PROTEIN-KINASE-C; WHITE-LIGHT INTERFEROMETRY; PEPTIDE NANOSTRUCTURES; DAG-LACTONES; NANOFIBERS; DERIVATIVES; MONOLAYERS; MECHANISM; FIBRILS; FILMS;
D O I：
10.1002/cphc.200900539
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Biomimetic pharmacophores deposited at the air/water interface self-assemble into distinct crystalline nanostructures (see figure). The shapes and dimensions of the nanostructures are significantly modulated by the lipid environments in mixed lipid/DAG-lactone monolayers © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：2615 / 2619
页数：5
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