Hepatoprotective iridoid glucosides from Callicarpa nudiflora

被引：24

作者：

Luo, Yue-Hua ^{[1
]}

Fu, Hui-Zheng ^{[1
]}

Huang, Bo ^{[1
]}

Chen, Wei-Kang ^{[1
]}

Ma, Shuang-Cheng ^{[2
]}

机构：

[1] Jiangxi Prov Inst Drug Control, Jiangxi Prov Engn Res Ctr Drug & Med Device Qual, Nanchang 330029, Peoples R China

[2] Natl Inst Food & Drug Control, Beijing 100050, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2016年 / 18卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Callicarpa nudiflora; Verbenacase; iridoid glucosides; hepatoprotective activity; CHEMICAL-CONSTITUENTS; GLYCOSIDES; ROOTS;

D O I：

10.1080/10286020.2015.1074572

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new iridoid glucosides, callicoside A (1) and callicoside B (2), were isolated from the leaves of Callicarpa nudiflora. Their structures were elucidated by means of spectroscopic methods and chemical evidences. In an in vitro bioassay, compound 1 showed pronounced hepatoprotective activity against D-galactosamine-induced toxicity in WB-F344 rat hepatic epithelial stem-like cells.

引用

页码：274 / 279

页数：6

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