Non-invasive glioblastoma immunoprofiling by printed peptide arrays

被引:3
作者
Mock, Andreas [1 ]
Herold-Mende, Christel [1 ]
机构
[1] Univ Heidelberg Hosp, Expt Neurosurg, Dept Neurosurg, Heidelberg, Germany
关键词
Antibodies; glioblastoma; long-term survival; non-invasive; biomarker; serum; TNC; TUMOR-ASSOCIATED ANTIGENS; SURVIVAL;
D O I
10.1080/2162402X.2015.1069941
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Immune monitoring assays for patient stratification and treatment efficacy in clinical trials are in demand. We have recently described a cost-effective non-invasive assay to determine the immune status of glioblastoma patients. Profiling antitumor serum antibodies by customized printed peptide arrays identified response against a tenascin-C (TNC) peptide as a robust prognostic biomarker.
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页数:3
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