The Effect of Pomegranate (Punica granatum L.) Byproducts and Ellagitannins on the Growth of Human Gut Bacteria

被引:130
作者
Bialonska, Dobroslawa [1 ,4 ]
Kasimsetty, Sashi G. [1 ]
Schrader, Kevin K. [3 ]
Ferreira, Daneel [1 ,2 ]
机构
[1] Univ Mississippi, Dept Pharmacognosy, Sch Pharm, University, MS 38677 USA
[2] Univ Mississippi, Natl Ctr Nat Prod Res, Res Inst Pharmaceut Sci, University, MS 38677 USA
[3] ARS, NPURU, USDA, University, MS 38677 USA
[4] Jagiellonian Univ, Inst Environm Sci, PL-30387 Krakow, Poland
关键词
Punica granatum L; byproduct; punicalagins; punicalins; ellagic acid; gallic acid; intestin pathogens probiotics; IN-VITRO; COLONIC MICROFLORA; JUICE CONSUMPTION; ELLAGIC ACID; HUMAN PLASMA; ANTIOXIDANT; POLYPHENOLS; PREBIOTICS; PHENOLICS; EXTRACT;
D O I
10.1021/jf901931b
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
The consumption of pomegranate products leads to a significant accumulation of ellagitannins in the large intestines here they interact with com le gut microflora his study in estigated the effect of pomegranate tannin constituents on the growth of various species of human gut bacteria Our results showed that pomegranate y products and unicalagins inhibited the growth of pathogenic clostridia and Staphyloccocus aureus. Probiotic lactobacilli and bifidobacteria were generally not affected y ellagitannins while relatively small growth inhibitior, y ellagic acid likely resulted from decreasing media duality due to the formation of tannin-protein complexes. The effect of pomegranate ellagitannins on Bifido bacteria as species and tannin dependent The growth of Bifidobacterium animalis ssp. lactis was slightly inhibited by punicalagins, punicalins, and ellagic acid supplementation significantly enhanced the growth of Bifidobacterium breve and Bifidobacterium, infantis.
引用
收藏
页码:8344 / 8349
页数:6
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