There's more than one way to scale a synapse

被引：10
作者：
Aizenman, Carlos D. [1 ]
Pratt, Kara G. [1 ]
机构：
[1] Brown Univ, Dept Neurosci, Providence, RI 02912 USA
来源：
NEURON | 2008年 / 58卷 / 05期
关键词：
D O I：
10.1016/j.neuron.2008.05.017
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
TNF alpha has been proposed to underlie synaptic scaling, but the mechanism and functional significance of this remain unclear. In this issue of Neuron, Cingolani et al. demonstrate that TNFa can mediate scaling through the regulation of beta 3 integrins. Kaneko et al. show that TNF alpha-dependent synaptic scaling plays an important role in visual cortical plasticity.
引用
收藏
页码：651 / 653
页数：3
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