Treatment of brain metastasis: current status and future directions

被引：8

作者：

Ruda, Roberta

Franchino, Federica

Soffietti, Riccardo ^{[1
,2
]}

机构：

[1] Univ Turin, Dept Neurooncol, Via Cherasco 15, I-10126 Turin, Italy

[2] City Hlth & Sci Hosp, Via Cherasco 15, I-10126 Turin, Italy

来源：

CURRENT OPINION IN ONCOLOGY | 2016年 / 28卷 / 06期

关键词：

brain metastasis; local treatments; targeted therapies; whole-brain radiotherapy; CELL LUNG-CANCER; GRADED PROGNOSTIC ASSESSMENT; HER2-POSITIVE BREAST-CANCER; STEREOTACTIC RADIOSURGERY BOOST; RADIATION-THERAPY; RANDOMIZED-TRIAL; PHASE-2; TRIAL; OPEN-LABEL; SURGICAL RESECTION; CEREBRAL METASTASES;

D O I：

10.1097/CCO.0000000000000326

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose of reviewThe purpose of this review is to highlight the most recent advances in the management of brain metastases.Recent findingsRole of local therapies (surgery and stereotactic radiosurgery), new approaches to minimize cognitive sequelae following whole-brain radiotherapy and advances in targeted therapies have been reviewed.SummaryThe implications for clinical trials and daily practice of the increasing use of stereotactic radiosurgery in multiple brain metastases and upfront targeted agents in asymptomatic brain metastases are discussed.

引用

页码：502 / 510

页数：9

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