Efficacy of desensitizing dentifrices to occlude dentinal tubules

被引:35
作者
Davies, Maria [1 ]
Paice, Elizabeth M. [1 ]
Jones, Sian B. [1 ]
Leary, Sam
Curtis, Andrew R. [1 ]
West, Nicola X. [1 ]
机构
[1] Univ Bristol, Sch Oral & Dent Sci, Clin Trials Grp, Bristol, Avon, England
关键词
arginine; citric acid; dentine hypersensitivity; dentine tubules; strontium; IN-VITRO; POTASSIUM-NITRATE; HYPERSENSITIVITY; TOOTHPASTES; PREVALENCE; FLUORIDE; SURFACE; SENSITIVITY; POPULATION; ENAMEL;
D O I
10.1111/j.1600-0722.2011.00872.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Dentine hypersensitivity occurs when patent dentinal tubules are subjected to external stimuli, with pain being reduced by products that occlude tubules. This study compared the efficacy of a recently developed arginine-containing dentifrice, two established strontium-based products, and a fluoride control to occlude tubules when subjected to acid challenge. Dentine specimens with patent tubules were divided into four groups that were treated with a slurry consisting of one of the pastes mixed with stimulated human saliva. Treated specimens were further subdivided and soaked in 0.3% citric acid for 10 s, 30 s, 2 min, 5 min or 10 min. Tubule occlusion on representative scanning electron microscopy images was scored by blind review. All three desensitizing pastes offered good tubule occlusion, which was maintained to varying degrees following acidic challenge. After immersion in acid for 10 and 30 s, the strontium acetate-and arginine-containing pastes almost fully occluded tubules, but only the strontium acetate paste retained this level of occlusion after immersion in acid for 2 min, with strong statistical evidence that this paste occluded more tubules than the other pastes after immersion in acid for 2 or 5 min. This suggests that strontium acetate pastes may be the most effective at reducing dentine hypersensitivity.
引用
收藏
页码:497 / 503
页数:7
相关论文
共 41 条
[1]   DENTIN HYPERSENSITIVITY - UPTAKE OF TOOTHPASTES ONTO DENTIN AND EFFECTS OF BRUSHING, WASHING AND DIETARY ACID - SEM IN-VITRO STUDY [J].
ABSI, EG ;
ADDY, M ;
ADAMS, D .
JOURNAL OF ORAL REHABILITATION, 1995, 22 (03) :175-182
[2]  
Addy Martin, 2010, J Clin Dent, V21, P25
[3]  
Ayad Farid, 2009, J Clin Dent, V20, P10
[4]   Dentine hypersensitivity: development and evaluation ofamodel in situ to study tubulepatency [J].
Banfield, N ;
Addy, M .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2004, 31 (05) :325-335
[5]  
Brannstrom M, 1967, CARIES RES, V1, P10
[6]   Prevalence of cervical dentine sensitivity in a population of patients referred to a specialist Periodontology Department [J].
Chabanski, MB ;
Gillam, DG ;
Bulman, JS ;
Newman, HN .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1996, 23 (11) :989-992
[7]   USE OF MULTIPLE SENSITIVITY MEASUREMENTS AND LOGIT STATISTICAL-ANALYSIS TO ASSESS THE EFFECTIVENESS OF A POTASSIUM-CITRATE-CONTAINING DENTIFRICE IN REDUCING DENTINAL HYPERSENSITIVITY [J].
CHESTERS, R ;
KAUFMAN, HW ;
WOLFF, MS ;
HUNTINGTON, E ;
KLEINBERG, I .
JOURNAL OF CLINICAL PERIODONTOLOGY, 1992, 19 (04) :256-261
[8]  
Cummins Diane, 2009, J Clin Dent, V20, P1
[9]  
Docimo Raffaella, 2009, J Clin Dent, V20, P17
[10]   AN IN-VITRO STUDY OF DENTINAL TUBULE OCCLUSION BY FERRIC OXALATE [J].
DRAGOLICH, WE ;
PASHLEY, DH ;
BRENNAN, WA ;
ONEAL, RB ;
HORNER, JA ;
VANDYKE, TE .
JOURNAL OF PERIODONTOLOGY, 1993, 64 (11) :1045-1051