The Benefits and Risks of Iron Supplementation in Pregnancy and Childhood

被引：107
作者：
Georgieff, Michael K. [1 ]
Krebs, Nancy F. [2 ]
Cusick, Sarah E. [1 ]
机构：
[1] Univ Minnesota, Sch Med, Dept Pediat, Minneapolis, MN 55454 USA
[2] Univ Colorado, Sch Med, Dept Pediat, Anschutz Med Campus, Aurora, CO 80045 USA
来源：
ANNUAL REVIEW OF NUTRITION, VOL 39, 2019 | 2019年 / 39卷
关键词：
iron; pregnancy; infancy; supplementation; neurodevelopment; malaria; BREAST-FED INFANTS; LOW-BIRTH-WEIGHT; RANDOMIZED CONTROLLED-TRIAL; RED-BLOOD-CELLS; DEFICIENCY ANEMIA; YOUNG-CHILDREN; ZINC SUPPLEMENTATION; PRETERM BIRTH; MATERNAL HEMOGLOBIN; INDONESIAN INFANTS;
D O I：
10.1146/annurev-nutr-082018-124213
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Iron deficiency is the most common micronutrient deficiency in the world and disproportionately affects pregnant women and young children. Iron deficiency has negative effects on pregnancy outcomes in women and on immune function and neurodevelopment in children. Iron supplementation programs have been successful in reducing this health burden. However, iron supplementation of iron-sufficient individuals is likely not necessary and may carry health risks for iron-sufficient and potentially some iron-deficient populations. This review considers the physiology of iron as a nutrient and how this physiology informs decision-making about weighing the benefits and risks of iron supplementation in iron-deficient, iron-sufficient, and iron-overloaded pregnant women and children.
引用
收藏
页码：121 / 146
页数：26
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