Expression patterns of proliferating cell nuclear antigen in trichloroacetic acid peeled skin

被引：7

作者：

Yamamoto, Yuki ^{[1
]}

Uede, Koji ^{[1
]}

Yonei, Nozomi ^{[1
]}

Furukawa, Fukumi ^{[1
]}

机构：

[1] Wakayama Med Univ, Dept Dermatol, Wakayama 6410012, Japan

来源：

JOURNAL OF DERMATOLOGY | 2007年 / 34卷 / 02期

关键词：

apoptosis; chemical peeling; proliferating cell nuclear antigen; trichloroacetic acid;

D O I：

10.1111/j.1346-8138.2006.00225.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

This study was designed to investigate whether trichloroacetic acid (TCA) peeling induces cellular proliferation in human skin using an immunohistochemical method. A 40% TCA peel resulted in a greater number of proliferating cell nuclear antigen (PCNA)-immunopositive cells in the whole epidermis as compared with 60% TCA or phenol peels. This finding suggests that long-term and frequent TCA peelings of low concentration would require special attention for unexpected cutaneous lesions such as skin tumors.

引用

页码：95 / 98

页数：4

共 9 条

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