Surface analysis using a new plasma assisted desorption/ionisation source for mass spectrometry in ambient air

被引:16
作者
Bowfield, A. [1 ,2 ]
Barrett, D. A. [3 ]
Alexander, M. R. [3 ]
Ortori, C. A. [3 ]
Rutten, F. M. [4 ,5 ]
Salter, T. L. [2 ]
Gilmore, I. S. [2 ]
Bradley, J. W. [1 ]
机构
[1] Univ Liverpool, Dept Elect Engn & Elect, Liverpool L69 3GJ, Merseyside, England
[2] Natl Phys Lab, Teddington TW11 0LW, Middx, England
[3] Univ Nottingham, Sch Pharm, Nottingham NG7 2RD, England
[4] Keele Univ, Sch Pharm, Keele ST5 5BG, Staffs, England
[5] Keele Univ, EPSAM, Keele ST5 5BG, Staffs, England
基金
英国工程与自然科学研究理事会;
关键词
DESORPTION ELECTROSPRAY-IONIZATION; ION-SOURCE; FORENSICS; PROBE; DESI;
D O I
10.1063/1.4729120
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
The authors report on a modified micro-plasma assisted desorption/ionisation (PADI) device which creates plasma through the breakdown of ambient air rather than utilising an independent noble gas flow. This new micro-PADI device is used as an ion source for ambient mass spectrometry to analyse species released from the surfaces of polytetrafluoroethylene, and generic ibuprofen and paracetamol tablets through remote activation of the surface by the plasma. The mass spectra from these surfaces compare favourably to those produced by a PADI device constructed using an earlier design and confirm that the new ion source is an effective device which can be used to achieve ambient mass spectrometry with improved spatial resolution. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4729120]
引用
收藏
页数:7
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