An electrochemical DNA biosensor based on the "Y" junction structure and restriction endonuclease-aided target recycling strategy

被引:41
作者
Wang, Qing [1 ]
Yang, Lijuan [1 ]
Yang, Xiaohai [1 ]
Wang, Kemin [1 ]
He, Leiliang [1 ]
Zhu, Jinqing [1 ]
Su, Tianyuan [1 ]
机构
[1] Hunan Univ, Key Lab Bionanotechnol & Mol Engn Hunan Prov, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
基金
对外科技合作项目(国际科技项目); 中国国家自然科学基金;
关键词
SEQUENCE-SPECIFIC DETECTION; SURFACE-PLASMON RESONANCE; NUCLEIC-ACIDS; FLUORESCENCE DETECTION; AMPLIFICATION; EXONUCLEASE; MICROARRAYS; PROBES; SENSOR;
D O I
10.1039/c2cc17679c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Based on the "Y'' junction structure and restriction endonuclease-aided target recycling strategy, an electrochemical biosensor for DNA detection was developed. This universal biosensor was suitable for detecting different sequences of target DNA by changing the sequence of capture and assistant strands.
引用
收藏
页码:2982 / 2984
页数:3
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