Synthesis of some novel 1-aminomethyl-3-benzoylhydrazono-2-indolinones as potential antiinflammatory agents

被引：0

作者：

Nagarapu, L ^{[1
]}

Ravirala, N ^{[1
]}

Akkewar, DM ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Ind Organ Chem 2, Hyderabad 500007, Andhra Pradesh, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 1998年 / 37卷 / 12期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acid-catalysed condensation of hydrazides 3, obtained from substituted phenoxybenzoic acids 1 with indolin-2,3-dione 4, results into hydrazono-2-indolinones 5. Compounds 5 when subjected to Mannich reaction with different cyclic secondary amines yield 1-aminomethyl-3-benzoylhydrazono-2-indolinones 6 (Mannich bases). All these compounds (6a-i) exhibit significant antiinflammatory activity.

引用

页码：1254 / 1257

页数：4

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