Synthesis and antimicrobial activities of novel 4H-1,4-benzothiazines and their sulfones

被引：0

作者：

Dixit, Rahul ^{[1
]}

Dixit, Yogesh ^{[1
]}

Gautam, Naveen ^{[2
]}

Gautam, D. C. ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

[2] LBS Govt PG Coll, Jaipur 303108, Rajasthan, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2008年 / 17卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An elegant one step synthesis of substituted 4H-1,4-benzothiazines 4 has been achieved by the condensation of substituted 2-aminobenzenethiols 1 with beta-diketones 2 in dimethyl sulfoxide. Compounds 4 on refluxing with 30% hydrogen peroxide in gl acetic acid undergo oxidation and afford their sulfones 5. All the synthesized compound have been characterized by IR, (1)H NMR, Mass spectra and elemental analysis and screened for their antibacterial and antifungal activities.

引用

页码：323 / 326

页数：4

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