Dementia with Lewy bodies presenting as Logopenic variant primary progressive Aphasia

被引：7

作者：

Boes, Samuel ^{[1
,2
]}

Botha, Hugo ^{[1
]}

Machulda, Mary ^{[3
]}

Lowe, Val ^{[4
]}

Graff-Radford, Jonathan ^{[1
]}

Whitwell, Jennifer L. ^{[4
]}

Utianski, Rene L. ^{[1
]}

Duffy, Joseph R. ^{[1
]}

Josephs, Keith A. ^{[1
]}

机构：

[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA

[2] Univ Minnesota, Coll Biol Sci, Minneapolis, MN USA

[3] Mayo Clin, Dept Psychiat & Psychol, Rochester, MN USA

[4] Mayo Clin, Dept Radiol, Rochester, MN USA

来源：

NEUROCASE | 2020年 / 26卷 / 05期

关键词：

Logopenic progressive aphasia; dementia with Lewy bodies; alzheimer disease; beta-amyloid (A beta); ALZHEIMERS; PATHOLOGY; SPEECH;

D O I：

10.1080/13554794.2020.1795204

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report a patient presenting with clinical features of logopenic variant primary progressive aphasia (lvPPA) who was later diagnosed with probable dementia with Lewy bodies. LvPPA is a neurodegenerative disease that is characterized by anomia, word-finding difficulty, impaired comprehension, and phonological errors. The most common underlying pathology for lvPPA is Alzheimer's disease. However, our patient with clinical features of logopenic progressive aphasia was later diagnosed with probable dementia with Lewy bodies. This case demonstrates that lvPPA can also be an initial manifestation of a phenotype of dementia with Lewy bodies.

引用

页码：259 / 263

页数：5

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