A new route to highly functionalized heterocyclic rings

被引：23

作者：

Parsons, Philip J. ^{[1
]}

Waters, Alexander J.

Walter, Daryl S.

Board, Johnathan

机构：

[1] Univ Sussex, Dept Chem, Sch Life Sci, Brighton BN1 9QJ, E Sussex, England

[2] GlaxoSmithKline Res & Dev Ltd, Harlow CM19 5AW, Essex, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 04期

关键词：

D O I：

10.1021/jo062305n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] A novel cascade reaction has been developed for the rapid construction of heterocyclic rings. The cyclization is thermally induced and does not involve the use of metal ions. This highly efficient construction of furans has been developed during studies directed toward the synthesis of the antibiotic lactonamycin 1.

引用

页码：1395 / 1398

页数：4

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