Antimalarial agents diminish while methotrexate, azathioprine and mycophenolic acid increase BAFF levels in systemic lupus erythematosus

被引:14
作者
Hernandez-Breijo, Borja [1 ]
Gomez, Alvaro [2 ,3 ]
Soukka, Sofia [2 ,3 ]
Johansson, Petter [2 ,3 ]
Parodis, Ioannis [2 ,3 ]
机构
[1] La Paz Univ Hosp, IdiPaz, Immunorheumatol Res Grp, Madrid, Spain
[2] Karolinska Inst, Dept Med Solna, Div Rheumatol, Stockholm, Sweden
[3] Karolinska Univ Hosp, Rheumatol, SE-17176 Stockholm, Sweden
基金
瑞典研究理事会;
关键词
Systemic lupus erythematosus; BAFF; BLyS; Antimalarial agents; Immunosuppressive agents; B-LYMPHOCYTE STIMULATOR; DISEASE-ACTIVITY; HYDROXYCHLOROQUINE; MECHANISMS; BELIMUMAB;
D O I
10.1016/j.autrev.2019.102372
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:4
相关论文
共 17 条
[1]   EULAR recommendations for the management of systemic lupus erythematosus. Report of a task force of the EULAR standing committee for international clinical studies including therapeutics [J].
Bertsias, G. ;
Ioannidis, J. P. A. ;
Boletis, J. ;
Bombardieri, S. ;
Cervera, R. ;
Dostal, C. ;
Font, J. ;
Gilboe, I. M. ;
Houssiau, F. ;
Huizinga, T. ;
Isenberg, D. ;
Kallenberg, C. G. M. ;
Khamashta, M. ;
Piette, J. C. ;
Schneider, M. ;
Smolen, J. ;
Sturfelt, G. ;
Tincani, A. ;
van Vollenhoven, R. ;
Gordon, C. ;
Boumpas, D. T. .
ANNALS OF THE RHEUMATIC DISEASES, 2008, 67 (02) :195-205
[2]  
Bosello S, 2008, J RHEUMATOL, V35, P1256
[3]  
Fox R, 1996, LUPUS, V5, pS4, DOI 10.1177/096120339600500103
[4]   A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus [J].
Furie, Richard ;
Petri, Michelle ;
Zamani, Omid ;
Cervera, Ricard ;
Wallace, Daniel J. ;
Tegzova, Dana ;
Sanchez-Guerrero, Jorge ;
Schwarting, Andreas ;
Merrill, Joan T. ;
Chatham, W. Winn ;
Stohl, William ;
Ginzler, Ellen M. ;
Hough, Douglas R. ;
Zhong, Z. John ;
Freimuth, William ;
van Vollenhoven, Ronald F. .
ARTHRITIS AND RHEUMATISM, 2011, 63 (12) :3918-3930
[5]   Distinct Effects of Methotrexate and Etanercept on the B Cell Compartment in Patients With Juvenile Idiopathic Arthritis [J].
Glaesener, Stephanie ;
Quach, Tam D. ;
Onken, Nils ;
Weller-Heinemann, Frank ;
Dressler, Frank ;
Huppertz, Hans-Iko ;
Thon, Angelika ;
Meyer-Bahlburg, Almut .
ARTHRITIS & RHEUMATOLOGY, 2014, 66 (09) :2590-2600
[6]   New concepts in antimalarial use and mode of action in dermatology [J].
Kalia, Sunil ;
Dutz, Jan P. .
DERMATOLOGIC THERAPY, 2007, 20 (04) :160-174
[7]   The role of antimalarial agents in the treatment of SLE and lupus nephritis [J].
Lee, Senq-J ;
Silverman, Earl ;
Bargman, Joanne M. .
NATURE REVIEWS NEPHROLOGY, 2011, 7 (12) :718-729
[8]  
Mahdy A. A., 2014, Bulletin of the Faculty of Pharmacy, Cairo University, V52, P37, DOI 10.1016/j.bfopcu.2014.01.002
[9]   Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial [J].
Navarra, Sandra V. ;
Guzman, Renato M. ;
Gallacher, Alberto E. ;
Hall, Stephen ;
Levy, Roger A. ;
Jimenez, Renato E. ;
Li, Edmund K-M ;
Thomas, Mathew ;
Kim, Ho-Youn ;
Leon, Manuel G. ;
Tanasescu, Coman ;
Nasonov, Eugeny ;
Lan, Joung-Liang ;
Pineda, Lilia ;
Zhong, Z. John ;
Freimuth, William ;
Petri, Michelle A. .
LANCET, 2011, 377 (9767) :721-731
[10]   Rituximab-mediated late-onset neutropenia in systemic lupus erythematosus - distinct roles of BAFF and APRIL [J].
Parodis, I. ;
Soder, F. ;
Faustini, F. ;
Kasza, Z. ;
Samuelsson, I. ;
Zickert, A. ;
Svenungsson, E. ;
van Vollenhoven, R. F. ;
Malmstrom, V. ;
Wermeling, F. ;
Gunnarsson, I. .
LUPUS, 2018, 27 (09) :1470-1478