Site-specific dynamics in DNA: Experiments

被引：41
|
作者：
Robinson, BH
Mailer, C
Drobny, G
机构：
[1] Department of Chemistry, University of Washington, Box 351700, Seattle
来源：
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE | 1997年 / 26卷
关键词：
DNA; dynamics; electron paramagnetic resonance (EPR); magnetic resonance; nuclear magnetic resonance (NMR); nucleic acid;
D O I：
10.1146/annurev.biophys.26.1.629
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This chapter reviews the dynamics information obtained from experimental magnetic resonance studies of site-specifically labeled duplex DNA. A previous review (43) discusses the dynamics of duplex DNA; it develops a theory that shows how magnetic resonance experiments are used to detect those dynamics. The methods for obtaining information about dynamics as well as a summary of what is now known about the site-specific dynamics of DNA are presented. This review contains two methods sections which present results using electron paramagnetic resonance and nuclear magnetic resonance active probes.
引用
收藏
页码：629 / 658
页数：30
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