Use of Cannabinoids for Spasticity and Pain Management in MS

被引：3

作者：

Chohan, Hardeep ^{[1
]}

Greenfield, Ariele L. ^{[1
]}

Yadav, Vijayshree ^{[2
]}

Graves, Jennifer ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol, 350 Parnassus Ave,304 A, San Francisco, CA 94117 USA

[2] Oregon Hlth & Sci Univ, Dept Neurol, Portland, OR 97201 USA

来源：

CURRENT TREATMENT OPTIONS IN NEUROLOGY | 2016年 / 18卷 / 01期

关键词：

Multiple sclerosis; Cannabinoids; Spasticity Pain; Tetrahydrocannabinol; Cannabidiol; GUIDELINE DEVELOPMENT SUBCOMMITTEE; MULTIPLE-SCLEROSIS; AMERICAN ACADEMY; MEDICAL MARIJUANA; CONTROLLED-TRIAL; PARALLEL-GROUP; DOUBLE-BLIND; EFFICACY; SAFETY; COMPLEMENTARY;

D O I：

10.1007/s11940-015-0385-y

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Several randomized trials have demonstrated potential benefit of cannabis derivatives in the symptomatic treatment of multiple sclerosis (MS) patients. These provide class 1 and 2 evidence for cannabinoid product use for spasticity and pain in these patients. The precise best ratio or doses are not yet clear. The safety and potential long-term effects of these products on cognitive function in people with MS have not been evaluated. Since short-term memory and processing speed can be significantly impaired in many people with MS, the concern of potential cognitive impairment related to cannabis products needs consideration in clinical care and should be addressed in longer, prospective studies.

引用

页码：1 / 14

页数：14

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