Protein functions in pre-mRNA splicing

被引：242
作者：
Will, CL
Luhrmann, R
机构：
[1] Inst. Molekularbiologie T., Philipps Universität Marburg, 35037 Marburg
来源：
CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 03期
关键词：
D O I：
10.1016/S0955-0674(97)80003-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Proteins have been implicated in an expanding variety of functions during pre-mRNA splicing. Molecular cloning has identified genes encoding spliceosomal proteins that potentially act as novel RNA helicases, GTPases, or protein isomerases. Novel protein-protein and protein-RNA interactions that are required for functional spliceosome formation have also been described. Finally, growing evidence suggests that proteins may contribute directly to the spliceosome's active sites.
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页码：320 / 328
页数：9
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