The current state of randomized clinical trial evidence for prostate brachytherapy

被引:9
作者
Dess, Robert T. [1 ]
Soni, Payal D. [2 ]
Jackson, William C. [1 ]
Berlin, Alejandro [3 ]
Cox, Brett W. [4 ]
Jolly, Shruti [1 ]
Efstathiou, Jason A. [5 ]
Feng, Felix Y. [6 ,7 ,8 ]
Kishan, Amar U. [9 ]
Stish, Bradley J. [10 ]
Pisansky, Thomas M. [10 ]
Spratt, Daniel E. [1 ]
机构
[1] Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
[2] Hunter Holmes McGuire VA Med Ctr, Dept Radiat Oncol, Richmond, VA USA
[3] Univ Toronto, Dept Radiat Oncol, Toronto, ON, Canada
[4] Northwell Hlth, Hofstra Northwell Sch Med, Dept Radiat Med, Hempstead, NY USA
[5] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA
[6] Univ Calif San Francisco, Dept Radiat Oncol, San Francisco, CA 94143 USA
[7] Univ Calif San Francisco, Dept Urol, San Francisco, CA 94143 USA
[8] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[9] Univ Calif Los Angeles, Dept Radiat Oncol, Los Angeles, CA 90024 USA
[10] Mayo Clin, Dept Radiat Oncol, Rochester, MN USA
关键词
Prostate cancer; Brachytherapy; LDR; HDR; Combination therapy; HIGH-DOSE-RATE; EXTERNAL-BEAM RADIATION; TERM ANDROGEN DEPRIVATION; SOCIETY CONSENSUS GUIDELINES; LOCALLY ADVANCED CANCER; CELL LUNG-CANCER; TROG; 03.04; RADAR; QUALITY-OF-LIFE; PHASE-II; AMERICAN BRACHYTHERAPY;
D O I
10.1016/j.urolonc.2019.04.009
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Interstitial brachytherapy is one of several curative therapeutic options for the treatment of localized prostate cancer. In this review, we summarize all available randomized data to support the optimal use of prostate brachytherapy. Evidence from completed randomized controlled trials is the focus of this review with a presentation also of important ongoing trials. Gaps in knowledge are identified where future investigation may be fruitful with intent to inspire well-designed prospective studies with standardized treatment that focuses on improving oncological outcomes, reducing morbidity, or maintaining quality of life. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码:599 / 610
页数:12
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