[1] Cardiff Univ, Sch Med, Cardiff CF10 3AX, S Glam, Wales
[2] Kings Coll London, Dept Immunobiol, London WC2R 2LS, England
[3] Guys & St Thomas Fdn Trust, Dept Endocrinol & Diabet, London, England
[4] Royal Victoria Infirm, Dept Endocrinol & Diabet, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[5] Bristol Royal Infirm & Gen Hosp, Joint Clin Res Unit, Bristol, Avon, England
[6] Natl Inst Hlth Res Diabet Res Network, New York, NY USA