Genetic Diversity of Trichomonas Vaginalis Clinical Isolates According to Restriction Fragment Length Polymorphism Analysis of the 60-kDa Proteinase Gene

被引：1

作者：

Hernandez, Hilda ^{[1
]}

Fraga, Jorge ^{[1
]}

Marcet, Ricardo ^{[1
]}

Alba, Annia ^{[1
]}

Figueredo, Mabel ^{[1
]}

Alfonso, Yenisey ^{[1
]}

Rojas, Lazara ^{[1
]}

Sarracent, Jorge ^{[1
]}

机构：

[1] Inst Trop Med Pedro Kouri, Dept Parasitol, AP 601 Marianao 13, Havana, Cuba

来源：

ACTA PARASITOLOGICA | 2019年 / 64卷 / 02期

关键词：

Trichomonas vaginalis; 60-kDa proteinase gene; Polymorphism; 62 KDA PROTEINASE; ACTIN GENE; RISK; SEQUENCE; HIV-1; DNA;

D O I：

10.2478/s11686-019-00065-5

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

IntroducctionTrichomonas vaginalis is a highly prevalent parasitic that causes the sexually transmitted disease trichomoniasis with some serious health complications. More understanding about genetic features of the parasite can be helpful in the study of the pathogenesis, epidemiology of the infection and drug susceptibility. For this end, we conducted analysis of a fragment (23kDa) of the p60 of T. vaginalis gene.Material and methodsThe restriction fragment length polymorphism (RFLP) methods was used.Result and discussionRFLP analysis showed the difference between T. vaginalis isolates from symptomatic and asymptomatic patients, suggesting a relation between the genetic identity of the isolates and their clinical manifestations.

引用

页码：300 / 307

页数：8

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