Cervical spine and muscle adaptation after spaceflight and relationship to herniation risk: protocol from 'Cervical in Space' trial

被引：1

作者：

Belavy, Daniel L. ^{[1
]}

Armbrecht, Gabriele ^{[2
]}

Albracht, Kirsten ^{[3
,4
]}

Brisby, Helena ^{[5
]}

Falla, Deborah ^{[6
]}

Scheuring, Richard ^{[7
]}

Sovelius, Roope ^{[8
]}

Wilke, Hans-Joachim ^{[9
]}

Rennerfelt, Kajsa ^{[10
]}

Martinez-Valdes, Eduardo ^{[6
]}

Arvanitidis, Michail ^{[6
]}

Goell, Fabian ^{[4
]}

Braunstein, Bjoern ^{[4
,11
]}

Kaczorowski, Svenja ^{[1
]}

Karner, Vera ^{[1
]}

Arora, Nitin Kumar ^{[1
]}

机构：

[1] Univ Appl Sci, Dept Appl Hlth Sci, Div Physiotherapy, Hochsch Gesundheit, Gesundheitscampus 6-8, D-44801 Bochum, Germany

[2] Charite Univ Med Berlin, Ctr Muscle & Bone Res, Hindenburgdamm 30, D-12203 Berlin, Germany

[3] Aachen Univ Appl Sci, Dept Med Engn & Technomath, Aachen, Germany

[4] German Sport Univ Cologne, Inst Movement & Neurosci, Sportpk Mungersdorf 6, D-50933 Cologne, Germany

[5] Sahlgrens Univ Hosp, Dept Orthoped Surg, S-41545 Gothenburg, Sweden

[6] Univ Birmingham, Ctr Precis Rehabil Spinal Pain CPR Spine, Sch Sport Exercise & Rehabil Sci, Coll Life & Environm Sci, Edgbaston B15 2TT, England

[7] NASA, Johnson Space Ctr, 2101 NASA Pkwy SD4, Houston, TX 77058 USA

[8] Satakunta Air Command, Ctr Mil Med, POB 761, Tampere 33101, Finland

[9] Univ Ulm, Helmholtzstr 14, D-89081 Ulm, Germany

[10] Sahlgrens Univ Hosp, Orthopaed & Spine Surg, Bruna Straket 11B, S-41345 Gothenburg, Sweden

[11] German Sport Univ Cologne, Inst Biomech & Orthopaed, Sportpk Mungersdorf 6, D-50933 Cologne, Germany

来源：

BMC MUSCULOSKELETAL DISORDERS | 2022年 / 23卷 / 01期

关键词：

Prolapse; Atrophy; Astronaut; Microgravity; Vertebrae; Disc prolapse; WHIPLASH-ASSOCIATED DISORDERS; SPATIAL-DISTRIBUTION; TREADMILL WALKING; DISC-DEGENERATION; EXTENSOR MUSCLES; ARM MOVEMENTS; NECK PAIN; COORDINATION; SHOULDER; DENSITY;

D O I：

10.1186/s12891-022-05684-0

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Background Astronauts have a higher risk of cervical intervertebral disc herniation. Several mechanisms have been attributed as causative factors for this increased risk. However, most of the previous studies have examined potential causal factors for lumbar intervertebral disc herniation only. Hence, we aim to conduct a study to identify the various changes in the cervical spine that lead to an increased risk of cervical disc herniation after spaceflight. Methods A cohort study with astronauts will be conducted. The data collection will involve four main components: a) Magnetic resonance imaging (MRI); b) cervical 3D kinematics; c) an Integrated Protocol consisting of maximal and submaximal voluntary contractions of the neck muscles, endurance testing of the neck muscles, neck muscle fatigue testing and questionnaires; and d) dual energy X-ray absorptiometry (DXA) examination. Measurements will be conducted at several time points before and after astronauts visit the International Space Station. The main outcomes of interest are adaptations in the cervical discs, muscles and bones. Discussion Astronauts are at higher risk of cervical disc herniation, but contributing factors remain unclear. The results of this study will inform future preventive measures for astronauts and will also contribute to the understanding of intervertebral disc herniation risk in the cervical spine for people on Earth. In addition, we anticipate deeper insight into the aetiology of neck pain with this research project.

引用

页数：11

共 45 条

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